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"The point sticks in your head: physics rules. Virtue does not triumph unless the physics allows it."
- Larry Niven

Mutation  
  An organism that has come into being through genetic mutation.  

This is the first use in sf, perhaps the first use anywhere, of "mutation" as a noun.

There would be super-men, bodiless heads, pure brains; only to be changed by the last mutation of all into the protoplasm from which first it had sprung!
From The Man Who Evolved, by Edmond Hamilton.
Published by Wonder Stories in 1931
Additional resources -

The end result:


(The Man Who Evolved)

Compare to mutant from The 100th Generation by Nat Schachner.

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Additional resources:
  More Ideas and Technology from The Man Who Evolved
  More Ideas and Technology by Edmond Hamilton
  Tech news articles related to The Man Who Evolved
  Tech news articles related to works by Edmond Hamilton

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