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"We follow the scientists around and look over their shoulders. They're watching their feet: provable mistakes are bad for them. We're looking as far ahead as we can, and we don't get penalized for mistakes."
- Larry Niven

Bone-Building Compounds  
  Combat heavy gravity on other planets by building greater bone density in workers and colonists.  

Earth's scientists solved the problem to some extent by devising rigid metallic clothing not unlike armor which would support the interior human structure against Jupiter's pull. Crane's men were also administered compounds devised by the biochemists for the rapid building of bone to strengthen the skeleton structure...
From A Conquest of Two Worlds, by Edmond Hamilton.
Published by Wonder Stories in 1932
Additional resources -

This is an early use of this idea, which finally came to fruition in real science in the form of medicines like Boniva, a biophosphonate drug used in the prevention and treatment of osteoporosis, which marks a loss of bone mineral density and an increased risk of fracture. Physicians have known about osteoporosis since the early 19th century, but it wasn't until the 1960's that an effective treatment was found.

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  More Ideas and Technology from A Conquest of Two Worlds
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