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"I realized there was a heavy-duty change coming in biology, and I could write a really compelling novel about catastrophic evolution, punctuated equilibrium."
- Greg Bear

Paralyzing Cone  
  A device that paralyzes the muscles.  

"He spoke, too, of the paralyzing cone that held me prisoner, a weapon which he had brought back from the atomic world, and revealed that he had another one on his person also. It was, he said, a ray that neutralized the electric messages in the nervous system, thus wiping out the commands of the brain in that system, so that while reflex actions like the breathing of the lungs and beating of the heart were unaffected, the conscious of the brain to the muscles were nullified, paralyzing those muscles.
From The Atomic Conquerors, by Edmond Hamilton.
Published by Weird Tales in 1927
Additional resources -

Compare to the paralysis ray from Satellite Five (1938) by Arthur K. Barnes, the paralysis bomb from If This Goes On... (1940) by Robert Heinlein and the para-beam from The Mechanical Monarch () by .

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Additional resources:
  More Ideas and Technology from The Atomic Conquerors
  More Ideas and Technology by Edmond Hamilton
  Tech news articles related to The Atomic Conquerors
  Tech news articles related to works by Edmond Hamilton

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