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"There was a time when one old eccentric guy with a notebook could do something important to science. Now even the resources of a major university are often not enough."
- Jerry Pournelle

Anadrenalin  
  Has the opposite effect of adrenalin.  

He even discovered a couple of new ones, especially one he calls "anadrenalin", because it has just the opposite effect of adrenalin. Instead of stimulating the heard violently, it retards the heart and the whole neural system to infinitesimal activity.
From A Race Through Time, by Donald Wandrei.
Published by Astounding Science Fiction in 1933
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