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"The first thing that's wrong with being a science-fiction writer today is that the present has caught up with the future and surpassed it."
- Peter Watts

Alcodote  
  A compound that maintains sobriety while drinking.  

An enjoyable use for this idea, beloved by sf fans.

He gave his coffee cup back to the robot and got to his feet. "Get a little rest, for a couple of hours. Then draw some aldodote-vitamin pills from the medic. As soon as things are secured, there'll be parties all over the ship, and we'll be expected to look in on every one of them, have a drink, and say 'Well done, boys.'"
From Space Viking, by H. Beam Piper.
Published by Analog in 1962
Additional resources -

Thanks to Winchell Chung at Project Rho for the tip on this item.

This idea has been popular for a long time. Compare with the sobriety ray from Lewis Padgett's 1942 story The Twonky. Compare to the killalc pills from Harry Harrison's 1970 novel The Stainless Steel Rat's Revenge.

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Additional resources:
  More Ideas and Technology from Space Viking
  More Ideas and Technology by H. Beam Piper
  Tech news articles related to Space Viking
  Tech news articles related to works by H. Beam Piper

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