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Youthful Brain With A Flip Of A Molecular Switch
The flip of a single molecular switch helps create the mature neuronal connections that allow the brain to bridge the gap between adolescent impressionability and adult stability. Now Yale School of Medicine researchers have reversed the process, recreating a youthful brain that facilitated both learning and healing in the adult mouse.
“These are the molecules the brain needs for the transition from adolescence to adulthood,” said Dr. Stephen Strittmatter. Vincent Coates Professor of Neurology, Professor of Neurobiology and senior author of the paper. “It suggests we can turn back the clock in the adult brain and recover from trauma the way kids recover.”
Readers of Analog recall the "Kitten" series by Jeffrey D. Kooistra; "Puff" [Analog, December 1993], "Fluffy" [Analog, June 1996], and "Snowball" [Analog, July 1996].
The plot: scientist invents cat that never ages beyond being a kitten. Never-ending kitten-itude leads to constant learning at a high rate leads to hyperintelligent kittens leads to murder.
Via Yale; thanks to Winchell Chung for the tip on the story.
By monitoring the synapses in living mice over weeks and months, Yale researchers have identified the key genetic switch for brain maturation a study released March 6 in the journal Neuron. The Nogo Receptor 1 gene is required to suppress high levels of plasticity in the adolescent brain and create the relatively quiescent levels of plasticity in adulthood. In mice without this gene, juvenile levels of brain plasticity persist throughout adulthood. When researchers blocked the function of this gene in old mice, they reset the old brain to adolescent levels of plasticity.
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Science Fiction
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Current News
Stargate $500 Billion Investment in Artificial Intelligence
'... an artificial intelligence equal to the human.'
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'Rayno folded up the microterm and tucked it back inside his jumper.'
Nano-Chainmail 2D Mechanically Interlocked Polymer
'Nemourlon armor of reasonable weight resists penetration by most fragments and any bullet that is not both reasonably heavy and fairly high-velocity.'
Anker's SOLIX Solar Umbrella Portable Power
As predicted by science fiction thirty-five years ago!
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'Several thousand of them formed the positioning grid on the rubble pile.'
AI-THu Shapeshifting Transformer Home
'Its slack walls tightened, bulged, were crossed by ripples and waves of movement.'
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'Norman... had never ridden any motorized device that lacked onboard steering and balance systems.'
Transparent 4K OLED Wireless TV From LG
You will note that HG Wells also figured out the aspect ratio of the future!
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'As though a switch had been turned off, the pain stopped...'
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'At the ringside opposite them a table had been removed to make room for a large transparent plastic capsule on wheels.'
Organic Non-Planar 3D Printing
'It makes drawings in the air following drawings...'
Your Window For Being A Tesla Optimus Remote Operator May Be Closing
'... he realized that the moving thing inside was - of course - a robot.'
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'Not since the time he rewired the delivery robot...'
Amazing Wheel Shapeshifting In Real Time
'Each spoke telescopes into sections.'
Drone With Face Recognition Could Hunt You
'The spotter descends, and we think it searches the vicinity, looking for the victim’s face...'
Jizai Arms 'Free Limbs' Wearable Cyborg Arms
'Guy named Otto Octavius winds up with eight limbs. Four mechanical arms welded right onto his body. What are the odds?'
