Youthful Brain With A Flip Of A Molecular Switch

The flip of a single molecular switch helps create the mature neuronal connections that allow the brain to bridge the gap between adolescent impressionability and adult stability. Now Yale School of Medicine researchers have reversed the process, recreating a youthful brain that facilitated both learning and healing in the adult mouse.

By monitoring the synapses in living mice over weeks and months, Yale researchers have identified the key genetic switch for brain maturation a study released March 6 in the journal Neuron. The Nogo Receptor 1 gene is required to suppress high levels of plasticity in the adolescent brain and create the relatively quiescent levels of plasticity in adulthood. In mice without this gene, juvenile levels of brain plasticity persist throughout adulthood. When researchers blocked the function of this gene in old mice, they reset the old brain to adolescent levels of plasticity.

“These are the molecules the brain needs for the transition from adolescence to adulthood,” said Dr. Stephen Strittmatter. Vincent Coates Professor of Neurology, Professor of Neurobiology and senior author of the paper. “It suggests we can turn back the clock in the adult brain and recover from trauma the way kids recover.”

Readers of Analog recall the "Kitten" series by Jeffrey D. Kooistra; "Puff" [Analog, December 1993], "Fluffy" [Analog, June 1996], and "Snowball" [Analog, July 1996].

The plot: scientist invents cat that never ages beyond being a kitten. Never-ending kitten-itude leads to constant learning at a high rate leads to hyperintelligent kittens leads to murder.

Via Yale; thanks to Winchell Chung for the tip on the story.

Scroll down for more stories in the same category. (Story submitted 3/27/2013)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 1 )

Related News Stories - (" Biology ")

Oil from Algae - Can It Be Done?
'We dump everything that's waste into the tanks, pump the oil off the top.' - Hal Clement, 1950.

Amazing 'Hybrid' Solar-Powered Sea Slug Does Photosynthesis
Thank goodness for Star Trek.

Should You Submit Your DNA To A Database?
Consumer DNA services are often inaccurate.

Humans Evolve Deep Diving Abilities
Sounds like '60s sci-fi to me.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Sex In Driverless Cars?
'...admirable for petting.'

Amazing Kepler Space Telescope Decommissioned By NASA
'Thus it came about that the search for a planetiferous sun... was not unduly prolonged...'

ODYSSEUS Solar-Powered Stratospheric Plane Flies Forever
'The planes flew continuously, twenty-four hours a day...'

Augmented and-or Virtual Reality Shoes From Google
'The auto-treadmill's bumps and gullies matched whatever terrain the goggles showed me...'

Soon, Your Tesla Will Follow You Like A Pet
'... follow him as faithfully as a well-trained hound.'

Chinese Watrix Gait Recognition Watching You Always
'... those pesky gait-recognition cameras.'

FlexPai Foldable Phone By Royole
'...A paper thin polycarbon screen unfurled.'

Bioreactor Helps Legless Frogs Get Their Jump Back
'An alien drug... Used by an insect race... It can repair bones and organs. It can grow new tissue."

Oh Yes, We're Building The Rotating Tower In Dubai
'Give me an old-fashioned tetragon on a central pivot every time.'

Xinhua AI Anchor Puts CGI Face To Automated News
'...a congeries of software agents.'

Wirewax Watching You Watch, Adjusting Your Experience
'He adjusted the n, the r and b knobs, and hopefully anticipated a turn for the better...'

LawGeex AI Beats 20 Top Lawyers
'The Law Society has strict rules on the use of pseudo-intelligent software - terrified of putting... its members out of work.'

ROAM Robotics Skiing Exoskeleton
'The real genius in the design is that you don't have to control the suit; you just wear it...'

MIT Headset Lets You Communicate Without Speaking
'The subvocal read nerve signals, letting her enter words by just beginning to will them...'

Exploring Oceans Across The Solar System
'Black liquid flashed past the turbot’s infrared eyes.'

SWEEPER Robot Peter Piper Picking Peppers
'... little machines, that went from plant to plant, apparently on caterpillar tracks, cutting off the ripe fruit.'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.