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Artificial Skin From Spain
Artificial skin generated by tissular engineering researchers from the University of Grenada has been successfully grafted onto mice and has shown generally positive results.
(Sewn into mice, the graft is accepted)
To create artificial human skin, human fibrin from plasma of healthy donors was used. Researchers then added tranexamic acid -to prevent fibrinolysis-, and calcium chloride to precipitate fibrin coagulation, and 0.1% aragose. These artificial-skin substitutes were grafted on the back of the nude mice, with the purpose of observing its evolution in vivo. The equivalent skin substitutes were analysed by transmission and scanning light and electron microscopy and inmunofluorescence.The skin created in the laboratory showed adequate biocompatibility rates with the recipient and no rejection, dehiscence or infection was registered. Additionally, the skin of all animals used in the study started to show granulation after six days from implantation. Within the following twenty days, cicatrization was complete.
This research was conducted by José María Jiménez Rodríguez, supervised by professors Miguel Alaminos Mingorance, Antonio Campos Muñoz and José Miguel Labrador Molina.
Artificial skin is a favorite of science fiction fans; see the surrogate skin from Robert Heinlein's 1951 novel The Puppet Masters and art-derm from Philip K. Dick's 1961 novel Dr. Futurity and the more functional read-out skin from John Varley's 1992 novel Steel Beach.
Looking for more real-life artificial skin alternatives? I've got you covered:
- Complete Human Skin Grown From Stem Cells
This advance could lead to production of one's own skin (an autologous transplant). - Artificial Skin Swatches Mass-Produced
Artificial skin is now in mass production at Germany's Fraunhofer-Gesellschaft science institute. - Skin Cells Genetically Modified To Fight Infection
“If we can add these genetically modified cells to bioengineered skin substitutes, it would provide an important defense system boost during the initial grafting period..." - Sensitive Artificial Skin For Humans, Not Robots
Now kindly DARPA boffins are making sure that human beings will also have sensitive artificial skin.
Scroll down for more stories in the same category. (Story submitted 4/21/2010)
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