Artificial Skin From Spain

Artificial skin generated by tissular engineering researchers from the University of Grenada has been successfully grafted onto mice and has shown generally positive results.

(Sewn into mice, the graft is accepted)

To create artificial human skin, human fibrin from plasma of healthy donors was used. Researchers then added tranexamic acid -to prevent fibrinolysis-, and calcium chloride to precipitate fibrin coagulation, and 0.1% aragose. These artificial-skin substitutes were grafted on the back of the nude mice, with the purpose of observing its evolution in vivo. The equivalent skin substitutes were analysed by transmission and scanning light and electron microscopy and inmunofluorescence.

The skin created in the laboratory showed adequate biocompatibility rates with the recipient and no rejection, dehiscence or infection was registered. Additionally, the skin of all animals used in the study started to show granulation after six days from implantation. Within the following twenty days, cicatrization was complete.

This research was conducted by José María Jiménez Rodríguez, supervised by professors Miguel Alaminos Mingorance, Antonio Campos Muñoz and José Miguel Labrador Molina.

Artificial skin is a favorite of science fiction fans; see the surrogate skin from Robert Heinlein's 1951 novel The Puppet Masters and art-derm from Philip K. Dick's 1961 novel Dr. Futurity and the more functional read-out skin from John Varley's 1992 novel Steel Beach.

Looking for more real-life artificial skin alternatives? I've got you covered:

From Eurekalert via MedGadget.

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