SPOT-NOSED Nanobiosensors For Doctors

The SPOT-NOSED (Single Protein Nanobiosensor Grid Array) project will ultimately result in "electronic noses" to help doctors detect and identify problems by odor.

The project was financed by the European Commission's FET (Future and Emerging Technologies) initiative. The nanobiosensors are constructed by placing a layer of olfactory receptor proteins from animal noses on a microelectrod; by measuring the reaction when the proteins come in contact with odorant molecules, the system can detect odorants in concentrations that humans would miss altogether.


(Nanobiosensor - single olfactory receptor)

Two olfactory receptors (ORs) of known ligand have been expressed in yeast (S. Cerevisiae). Both receptors are localised at the plasmic membrane of the yeast cell, and a functional response to the preferential odorant has been measured in the cell. In order to transfer those receptors to the nanobiosensor, nanosomes have been prepared from the cells membrane fraction, with sizes ranging from 60nm to 40nm.
(From SPOT-NOSED)

A nanobiosensor-based electronic nose would require, at minimum, several hundred different proteins; different proteins react to different odorants. The human nose, for example, uses about 1,000 different proteins to allow the brain to determine 10,000 different smells.

This method could lead to a new and quicker way to test for the presence of disease processes in urine, blood, pus or other bodily excretions from patients. In addition, smell technology could sense rotten food, explosives, or drugs.

An electronic nose, or sniffer robot was featured in the 1985 movie Runaway, written and directed by Michael Crichton.

The project was financed by the European Commission's FET (Future and Emerging Technologies) initiative. The nanobiosensors are constructed by placing a layer of olfactory receptor proteins from animal noses on a microelectrod; by measuring the reaction when the proteins come in contact with odorant molecules, the system can detect odorants in concentrations that humans would miss altogether.


(Sniffer robot from the movie Runaway)

In the film, a man is shot using a missile-like bullet; the sniffer robot is brought in to find out more. The crime scene technician interprets the results:

"It's picking up diphenyl compounds and tetrahydrocarbons. The tetras are explosives and the diphenyls are solid propellant like those used in rockets. How big did you say these missiles are?"
(Read more about sniffer robots)

I admit that I thought this was far-fetched when I saw this movie in the theater twenty years ago; now I'm not so sure.

Those with a nose for odor-related news may enjoy dogs sniff for cancer, the odor alarm clock and the Banryu guard dragon robot. Also, I'd like to recommend this April Fool's Day article on Google AdCense can improve olfactory relevancy. Read more about nanobiosensors; take a look at the SPOT-NOSED website.

Scroll down for more stories in the same category. (Story submitted 5/15/2006)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 1 )

Related News Stories - (" Medical ")

Organaut! Russians 3D Print Living Tissue In Space
'For a while your colonists will have to come up [to orbit] to the Hospital...' - Larry Niven, 1968.

MIT Scientists Create 'Peek-a-Boo Prober' From Jetsons
Well, George, it's the latest thing.

Wound Healing With Wearable Nanogenerators
'... forcing the energy transfer which allowed him to ... erase the other internal-external damage.' - Frank Herbert, 1972.

EXPLORER, The First Total-Body Scanner
'The object is built up of an infinite series of plane layers, at the focus of the ray...' - Jack Williamson, 1930.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Spicy Tomatoes Created With Genetic Engineering
How about mashed potatoes and brown gravy?

Driverless Hotel Rooms Predicted In 1828
'Did you never see a moving house before?'

Yandex Self-Driving Taxi Is Very Smooth
'The big car was slowing down, its computer brain sensing an exit ahead.'

Shrimp Actually Made Of Algae Is A New Wave Food
Bring in that crop algae.

Cosplay Style Wings Could Work On Moon
'They're lovely! - titanalloy struts as light and strong as bird-bones...'

Tesla Model 3 Has Outside Speaker Grille
Robert Heinlein does it again.

Arizona Luddites Attack Self-Driving Vehicles
'Trucks don't drive by themselves...' Or do they?

Organaut! Russians 3D Print Living Tissue In Space
'For a while your colonists will have to come up [to orbit] to the Hospital...'

WINE Spacecraft To Extract Water From Asteroids
'Yes, strangely enough there was still sufficient water beneath the surface of Vesta.'

Japanese Swordsmiths Take On Asteroids
'... a tiny, rocket-powered projectile, drove towards the mysterious bulk.'

Saturn's Rings To Vanish, Let's Mine Them While We Can
'...the valuable shards of what had once been satellites.'

Humans Could Take Up A LOT Less Space
We'd have a lot more room for gardening...

Implosion Fabrication Shrinks 3D Objects To Nanoscale
'Carter had watched miniaturization a hundred times...'

GMO Houseplant Cleans Your Air
Removes compounds too small to be captured by a HEPA filter.

Nova Meat Can 3D Print Your Dinner
Printing out chicken nuggets.

MIT Scientists Create 'Peek-a-Boo Prober' From Jetsons
Well, George, it's the latest thing.

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.