Bio Ink Jet Printing Muscle And Bone
Many people suffer with parts of their bodies that are just worn out, like hips and knees, or are damaged by disease processes, like arthritic joints. The first steps in being able to create complex body structures have been taken by researchers at Carnegie Mellon and the University of Pittsburgh. The results were presented on December 10th at the 46th annual meeting of the American Society for Cell Biology in San Diego.
A unique ink-jet printing system using bio-ink that can lay down a pattern of cells that will differentiate into a designed pattern of both bone and muscle cells has been created by a team of scientists from the two universities.
The researchers began with a glass slide with a layer of nurturing proteins as a base. They then used a robotic inkjet-style machine to lay down a specific pattern of tiny droplets of various proteins.
"It is like laying ink on paper," researcher Julie Jadlowiec Phillippi said. "It's a blueprint for cells to live and grow and differentiate with."
Then the muscle-derived stem cells (MDSCs) from mice were placed on top of this pattern to grow. "Depending on which pattern they are on top of, they become one lineage or another," she remarked.
This system is the first that can lay down a pattern of multiple cell types within the same vessel from a single population of adult stem cells. This system could one day benefit millions of people whose tissues have been damaged from genetic diseases, accidental trauma and even wear-and-tear from aging joints.
"Our findings showed that we successfully engineered MDSCs (muscle-derived stem cells) to become subpopulations of muscle or bone-like cells that were patterned using our bio-ink-jet system," said Phillippi. "This experiment represents a key first step in demonstrating the potential of this technology to learn more about not only the basic biology of how multiple cell types are patterned in the body during development, repair and regeneration, but also for translating adult stem cells into real therapies for patients in the future."
Because the ink-jet system employs such precision, it could be used one day to co-culture multiple MDSC lineages - including bone, muscle and other cell types - in complex, patterned configurations that could be incorporated directly into specific areas of the body in need of repair of multiple tissue types.
Take a look at this article on printing biomaterials with modified ink-jet printers for more about this technology.
Interested in futuristic medical advances?
Via "Inkjet" printer helps organize stem cells and Muscle and bone from an ink-jet printer.
Scroll down for more stories in the same category. (Story submitted 12/10/2006)
Follow this kind of news @Technovelgy.
| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
you like to contribute a story tip?
Get the URL of the story, and the related sf author, and add
Comment/Join discussion ( 4 )
Related News Stories -
You'll Regrow That Limb, One Day
'... forcing the energy transfer which allowed him to regrow his lost fingers.' - Frank Herbert, 1972.
First 3D Printed Human Corneas From Stem Cells
Just what we need! Lots of spare parts.
Nanorobots Roam Your Bloodstream, Cleaning It
Too bad they won't have lasers, though...
MIT Ampli Blocks Build Biomedical Devices
Damn it Spock, I'm a doctor not an engineer!
Technovelgy (that's tech-novel-gee!)
is devoted to the creative science inventions and ideas of sf authors. Look for
the Invention Category that interests
you, the Glossary, the Invention
Timeline, or see what's New.
LA Subway Scanner, As Seen In 'Total Recall'
'I'm afraid to tell you this Mr. Quaid, but you have suffered a schizoed embolism...'
Sion Electric Car Covered With Solar Panels
'It drew its power from six square yards of sunpower screens on its low curved roof.'
PAL-V Liberty Flying Helicopter Car
'...lifted themselves to skimming flight upon whirling helicopters."
Space Drones - UK's Effective Space To Launch Rocket Tugs
'Twenty rocket tugs towed it from its Earth hangar out into space.'
DIY Autonomous Robot Detects Trash
'The search-bug detached itself and rolled forward.'
Ancient Russian Walking Excavator Would Be Perfect RV
I don't need it to go fast, it just needs to amble along.
ELROI Satellite 'License Plate'
Robert Heinlein was thinking about this in 1941.
When Robots Beg For Their Lives
"Just what do you think you're doing... Dave.'
Do You Still Want A Folding Screen Phone?
'A paper thin polycarbon screen unfurled...'
'Snapchat Dysmorphia' Now A Thing, Say Plastic Surgeons
'The program raced up the screen one scan line at a time, subtly smoothing, deleting and coloring.'
Quiet Electric Cars Law Finalized By US Transportation Department
'... a sound tape to supply the noise'
Drone Assassin Fails To Kill Venezuelan President
'The spotter descends, and we think it searches the vicinity, looking for the victim's face...'
Stick-On Tape Speakers, As Predicted By Bruce Sterling
Flexible tape speakers, someday.
Bezos Invites You To New Life In Off-World Colonies
'A new life awaits you!'
Amazon's Rekognition System Sees Criminals In Congress
'... the imprint of her image on the telephoto cell.'
Build Your Own Space Suit For Cheap
'I'm going to pump the air from this room... so that the interior will be like airless and pressure-less space.'
More SF in the News Stories
More Beyond Technovelgy science news stories