Anti-Viral Polymer Paints Flu Into A Corner
A remarkable anti-viral polymer can be applied like paint; it was developed by MIT's Alexander Klibanov. His intent is to develop a biocidal "paint" that can help reduce the spread of germs in public areas and hospitals.
(Bottom slide covered with alkylated PEI)
In the above illustration, a regular commercial glass slide (top) and another one coated with alkylated PEI "paint" (bottom) were sprayed with aqueous suspensions of Staphylococcus aureus cells, and then incubated. Some 200 bacterial colonies are seen on the unprotected slide—and only 4 on the protected one.
Staphylococcus aureus is described by the CDC as a "superbug" that is resistant to many types of antibiotics. Studies have shown that it can survive for weeks even on hard surfaces.
Our recent studies have resulted in a new, “non-release” strategy for rendering common materials (plastics, glass, textiles) permanently microbicidal. This strategy, involving covalent attachment of certain long, moderately hydrophobic polycations to material surfaces, has been proven to be very effective against a variety of pathogenic bacteria and fungi, both airborne and waterborne. This work continues along with a quest for creating material coatings with anti-viral and anti-sporal activities.
Klibanov and his colleagues found that the prickly polymer worked on bacteria; they tested it with the smaller flu virus and found the same effects. They applied droplets of a flu solution to glass slips painted with the polymer. After a few minutes' exposure, they were unable to recover any active virus from the samples, meaning the coating reduced the pathogen's abundance by at least a factor of 10,000.
How does it work? In the case of bacteria, the polymer seems to gouge holes in a microbe's cell wall and spilling out its contents. The polymer molecules stay rigid because they are all positively charged and repel each other; they are like strands of hair standing on end from a static charge. The spikes have sufficiently few charges, however, that they can breach bacterial walls, which repel strongly charged molecules. The polymer probably neutralizes flu because the virus has an envelope around it suitable for spearing, Klibanov says.
Here are some other inventions that work on small organisms:
From Scientific American via MedGadget; read more about Alexander Klibanov.
Scroll down for more stories in the same category. (Story submitted 11/16/2006)
Follow this kind of news @Technovelgy.
| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
you like to contribute a story tip?
Get the URL of the story, and the related sf author, and add
Comment/Join discussion ( 0 )
Related News Stories -
Sleeep PRO Earplug For Maximum Rest
'Merton... placed the electrodes of the sleep-inducer on his forehead.' - Arthur C. Clarke, 1963.
You'll Regrow That Limb, One Day
'... forcing the energy transfer which allowed him to regrow his lost fingers.' - Frank Herbert, 1972.
First 3D Printed Human Corneas From Stem Cells
Just what we need! Lots of spare parts.
Nanorobots Roam Your Bloodstream, Cleaning It
Too bad they won't have lasers, though...
Technovelgy (that's tech-novel-gee!)
is devoted to the creative science inventions and ideas of sf authors. Look for
the Invention Category that interests
you, the Glossary, the Invention
Timeline, or see what's New.
Jaguar I-Pace Audible Vehicle Alert System For EVs
'Of course not a vehicle moved by means of internal explosions of a derivative of rock oil...'
Autonomous 'Fiberbots' Weave Large Structures
'It extrudes material like a spider.'
Birds Aren't Real - Wake Up, California! (With Bird Watching Guide)
'When he had first built them, they had been crude indeed, flying mechanisms with little more than a reflex-response unit.'
Self-Healing Material Pulls Carbon Out Of The Air
'... could seal the punctures.'
IRL Glasses Block Screens, Limit Vision To Real Life
'If you couldn't see the ads, how would you know what was fashionable?'
Testing The Single-Person Spacecraft
'...the lower part of the suit was simply a rigid cylinder.'
Shapeshifting Materials Transform By Light
'Its lines wavered, flowed, and then painfully reformed.'
Fully Automated Farm Iron Ox Hydroponics
'Had these machines in some incredible fashion been provided with brains?'
BrainNet Social Network Of Brains
'I used my implant to tell MILLIE what we wanted and she took care of it'
Phil Nuyttnn's City Under The Sea
'Under the lower roof there was no water, but a clear and luminous atmosphere...'
IONITY Opens First 10 Fast-Charging Stations
'Recharge the batteries... in almost every town and village...'
Superstrong Multilayer Metal-Graphene Composite Material
Negligible increase in weight increased material strength by hundreds of times.
Deepfakes Imperil Democracy (George Orwell, Right Again)
'All history was a palimpsest, scraped clean and reinscribed exactly as often as was necessary.'
String Art Courtesy Of Robot Artist
The number of different ways to span a thread between a larger number of hooks is astronomical.
Still Wondering If You'd Work For A Robot Boss?
'This is all coming to you courtesy of the simstim unit wired into your deck, of course.'
World's First Autonomous Tram In Germany
What's it like for autonomous trams when they're turned off at night?
More SF in the News Stories
More Beyond Technovelgy science news stories