3D Printed Replacement Tissue

Remarkable experiments demonstrate the ability to 3D print replace damaged or diseased tissue.


(3D printed ear)

A challenge for tissue engineering is producing three-dimensional (3D), vascularized cellular constructs of clinically relevant size, shape and structural integrity. We present an integrated tissue–organ printer (ITOP) that can fabricate stable, human-scale tissue constructs of any shape.

Mechanical stability is achieved by printing cell-laden hydrogels together with biodegradable polymers in integrated patterns and anchored on sacrificial hydrogels. The correct shape of the tissue construct is achieved by representing clinical imaging data as a computer model of the anatomical defect and translating the model into a program that controls the motions of the printer nozzles, which dispense cells to discrete locations. The incorporation of microchannels into the tissue constructs facilitates diffusion of nutrients to printed cells, thereby overcoming the diffusion limit of 100–200 μm for cell survival in engineered tissues.

We demonstrate capabilities of the ITOP by fabricating mandible and calvarial bone, cartilage and skeletal muscle. Future development of the ITOP is being directed to the production of tissues for human applications and to the building of more complex tissues and solid organs.

I've found a couple of early science fiction works that point to this work. In his epochal play R.U.R. (Rossum's Universal Robots), Karel Capek describes the factories in which the bones, organs, veins and other tissues for organic robots (we'd probably call them androids) are manufactured:

The spinning mill for nerves. The spinning mill for veins. The spinning mill where miles and miles of digestive tract are made at once. Then there's the assembly plant where all of this is put together, you know, like automobiles. Each worker is responsible for affixing one part, and then it automatically moves on to a second worker, then to a third, and so on.
(Read more about the spinning mill for veins)

As far as 3D printing living tissue is concerned, I ran across a fascinating description of a process for teleportation in The Cosmic Express, a 1930 story by Jack Williamson:

...In a parallel manner, the focal plane of the Express Ray moves slowly through the object, progressively, dissolving layers of the thickness of a single atom, which are accurately reproduced at the other focus of the instrument--which might be in Venus!

"But the analogy of the lens is the better of the two. For no receiving instrument is required, as in television. The object is built up of an infinite series of plane layers, at the focus of the ray,
(Read more about Cosmic Express)

This is exactly how 3D printing works: objects are built up, one plane layer at a time.

It amazes me that these ideas have been floating around for a long time, close to a century, and they're coming true in our lifetimes.

Via A 3D bioprinting system to produce human-scale tissue constructs with structural integrity.

Scroll down for more stories in the same category. (Story submitted 2/14/2016)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Medical ")

BrainEx Restores Some Activity To Severed Pig Head
'... they placed the brain in a special solution, having all the properties of Nursing the brain cells.' - Edmond Hamilton, 1929.

Purdue Pharma Ready To Profit From OxyContin Use Or Addiction Recovery
'It may be organic damage. It may be permanent. Time'll tell, and only after you are off Substance D for a long while.' - Philip K. Dick, 1977.

Organaut! Russians 3D Print Living Tissue In Space
'For a while your colonists will have to come up [to orbit] to the Hospital...' - Larry Niven, 1968.

MIT Scientists Create 'Peek-a-Boo Prober' From Jetsons
Well, George, it's the latest thing.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Datagrid Model Generation Perfect For Eternal Cities Of Science Fiction
'... there was enough flexibility to allow for wide variation.

Kazahk Ironist Protester Arrested For Blank Sign Protest
'...a man carried a white rectangular sign, blank on both sides.'

Bitcoin Surges Again, To $7,000
'... electronic, private cash, unbacked by any government, untraceable, completely anonymous.'

China Develops Taste Testing Robots
'Install taste buds in the end of one tentacle...'

North Sea Stone Age Reconstruction And Philip K Dick
'Your Dip digs back into antiquity. Rome. Greece. Dust and old volumes.'

Tesla Robotaxis Will Automatically Recharge Themselves
'Then it appeared to make up its mind, and trundled over to a wall socket...'

New Lifelike Material Powered By Artificial Metabolism
'... The biological robots were not living creatures.'

Husqvarna Automower 435X AWD
'Gramp Stevens sat in a lawn chair, watching the mower at work...'

Elon Musk Foretells Tesla Sans Steering Wheel
'How about the steering wheel... I don't need one.'

Adversarial Patches Trick Computer Vision
'The surveillance cameras can all see it, but then they forget they’ve seen it.'

Amazon Warehouse Computer Can Fire People Now
'The system has already fired five people...'

BrainEx Restores Some Activity To Severed Pig Head
'... they placed the brain in a special solution, having all the properties of Nursing the brain cells.'

Yes, But Do Astrobees Have Lasers For Lightsaber Training?
'... Ancient weapons are no match for a good blaster at your side, kid.'

'Young Razorbacks Before Their Katanas Grow In'
'Twin robotic arms with gleaming three-foot sword blades unfolded from the forward hydraulic assemblies...'

A New Way To Run Into Things
'He made an adjustment, pointed the tube at the wall beside Etzwane, and projected a cone of light.'

'Metallic Wood' Strong Like Titanium, Floats In Water
'A metal... light as cork and stronger than steel...'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.