Super-Strong Mouse 'Augments'

Super-strong mice with twice the muscular strength as average mice have been created by researchers from the Salk Institute for Biological Studies and two Swiss institutions, Ecole Polytechnique Federale de Lausanne (EPFL) and the University of Lausanne.

The team created the super-strong high endurance creatures by suppressing a natural muscle growth inhibitor. Genome regulator NCoR1 is a molecular brake that decreases activity of certain genes. This brake can be "released" through mutation or using chemicals and this, in turn, reactivates gene circuits to provide more energy to muscle and enhance its activity. This lead to the creation of super mice with muscles that are twice as strong as those of regular mice, even when the muscle was inactive.

Ronald M Evans, a professor at Salk's Gene Expression Lab, says: "There are now ways to develop drugs for people who are unable to exercise due to obesity or other health complications, such as diabetes, immobility and frailty. We can now engineer specific gene networks in muscle to give the benefits of exercise to sedentary mice."

Sedentary sf readers have flexed their mental muscles by being exposed to the idea of augments in the Star Trek universe. In the original series, Khan Noonien Singh is the leader of a group of Augments, the products of genetic engineering that were far stronger and smarter than ordinary humans.


(Khan, played by the incomparable Ricardo Montalban)

The real-life research on mice will hopefully lead to helpful treatments, not Eugenics Wars:

Johan Auwerx, the lead author from EPFL, said: "This could be used to combat muscle weakness in the elderly, which leads to falls and contributes to hospitalisations. In addition, we think that this could be used as a basis for developing a treatment for genetic muscular dystrophy."

From Wired UK; thanks to Moira for contributing the tip on this story.

Scroll down for more stories in the same category. (Story submitted 1/8/2012)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 2 )

Related News Stories - (" Medical ")

iFlytek Doctor Robot First To Pass Medical Exams
No problem, we'll just use the autodoc.

Watch What People Are Seeing Via Brain Scanning
'had managed to see through the other man's eyes as the other man, all unaware, washed their Zis limousine sixteen hundred meters away...' - Cordwainer Smith, 1958.

PRIMA Bionic Vision Restoration
'The VISOR... was a medical device used in the Federation to aid patients who have suffered loss of eyesight...'

Targeted Neuroplasticity Training For 'Downloading Skills'
'I know kung-fu.'

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

A 'Genuine Nanorobotic Production Factory'
'Microscopic machinery, smaller than ants, smaller than pins, working energetically, purposefully - constructing something...'

Neuromorphic Computer Offers Non-von Neumann Architecture
Fires faster than brain at 1/10K energy.

Evorus Your Crowd-Powered Conversational Assistant
'...the DS [Daily Schedule] was suddenly transformed into a valued confidante.'

Mealworms Food Of The Future
Get your grubs on.

Alibaba's AI May Read Better Than You
'Mike ... could accept other languages and was doing technical translating - and reading endlessly.'

Musk's Boring Flamethrower
'Skeletons in tatters. Burned by a flesh gun'

Humanity Star LEO Advertisement?
'Everyone has noticed those enormous advertisements...'

Nissan ProPILOT Slippers Are Self-Parking, Autonomous
Beyond science and fiction.

Atomristors - Atomic Memristors - Using Thin Nanomaterials
'I could almost feel those little tunnel junction neuristors working, forming their own interconnections as I operated it.'

Bigelow Prepares Inflatable Lunar Hotel
'Suddenly, hitherto unheard-of sums of money became available for investment in civilian orbital stations.'

Drunk Driver Of Tesla Claims Autopilot Was In Charge
'Mr. Garden, you are in no condition to drive.'

Medical Exoskeleton From Cyberdyne Gets FDA Approval
It's been a long road for HAL-5; I started writing about it in 2005.

Fungi-Infused Concrete Repairs Itself
'I noticed that curious mottled knots were forming, indicating where the room had been strained and healed faultily.'

Shiftwear Display Shoes
'He unlaced her shoe and glanced at its readout.'

NASA SEXTANT First With X-Ray Nav In Space
'You need at least four beacons for an accurate fix.'

GM Introduces Cruise AV With No Steering Wheel
'How about the steering wheel?' ... 'I do not need one.'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.