Super-Strong Mouse 'Augments'

Super-strong mice with twice the muscular strength as average mice have been created by researchers from the Salk Institute for Biological Studies and two Swiss institutions, Ecole Polytechnique Federale de Lausanne (EPFL) and the University of Lausanne.

The team created the super-strong high endurance creatures by suppressing a natural muscle growth inhibitor. Genome regulator NCoR1 is a molecular brake that decreases activity of certain genes. This brake can be "released" through mutation or using chemicals and this, in turn, reactivates gene circuits to provide more energy to muscle and enhance its activity. This lead to the creation of super mice with muscles that are twice as strong as those of regular mice, even when the muscle was inactive.

Ronald M Evans, a professor at Salk's Gene Expression Lab, says: "There are now ways to develop drugs for people who are unable to exercise due to obesity or other health complications, such as diabetes, immobility and frailty. We can now engineer specific gene networks in muscle to give the benefits of exercise to sedentary mice."

Sedentary sf readers have flexed their mental muscles by being exposed to the idea of augments in the Star Trek universe. In the original series, Khan Noonien Singh is the leader of a group of Augments, the products of genetic engineering that were far stronger and smarter than ordinary humans.


(Khan, played by the incomparable Ricardo Montalban)

The real-life research on mice will hopefully lead to helpful treatments, not Eugenics Wars:

Johan Auwerx, the lead author from EPFL, said: "This could be used to combat muscle weakness in the elderly, which leads to falls and contributes to hospitalisations. In addition, we think that this could be used as a basis for developing a treatment for genetic muscular dystrophy."

From Wired UK; thanks to Moira for contributing the tip on this story.

Scroll down for more stories in the same category. (Story submitted 1/8/2012)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 2 )

Related News Stories - (" Medical ")

Sleeep PRO Earplug For Maximum Rest
'Merton... placed the electrodes of the sleep-inducer on his forehead.' - Arthur C. Clarke, 1963.

You'll Regrow That Limb, One Day
'... forcing the energy transfer which allowed him to regrow his lost fingers.' - Frank Herbert, 1972.

First 3D Printed Human Corneas From Stem Cells
Just what we need! Lots of spare parts.

Nanorobots Roam Your Bloodstream, Cleaning It
Too bad they won't have lasers, though...

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Jaguar I-Pace Audible Vehicle Alert System For EVs
'Of course not a vehicle moved by means of internal explosions of a derivative of rock oil...'

Autonomous 'Fiberbots' Weave Large Structures
'It extrudes material like a spider.'

Birds Aren't Real - Wake Up, California! (With Bird Watching Guide)
'When he had first built them, they had been crude indeed, flying mechanisms with little more than a reflex-response unit.'

Self-Healing Material Pulls Carbon Out Of The Air
'... could seal the punctures.'

IRL Glasses Block Screens, Limit Vision To Real Life
'If you couldn't see the ads, how would you know what was fashionable?'

Testing The Single-Person Spacecraft
'...the lower part of the suit was simply a rigid cylinder.'

Shapeshifting Materials Transform By Light
'Its lines wavered, flowed, and then painfully reformed.'

Fully Automated Farm Iron Ox Hydroponics
'Had these machines in some incredible fashion been provided with brains?'

BrainNet Social Network Of Brains
'I used my implant to tell MILLIE what we wanted and she took care of it'

Phil Nuyttnn's City Under The Sea
'Under the lower roof there was no water, but a clear and luminous atmosphere...'

IONITY Opens First 10 Fast-Charging Stations
'Recharge the batteries... in almost every town and village...'

Superstrong Multilayer Metal-Graphene Composite Material
Negligible increase in weight increased material strength by hundreds of times.

Deepfakes Imperil Democracy (George Orwell, Right Again)
'All history was a palimpsest, scraped clean and reinscribed exactly as often as was necessary.'

String Art Courtesy Of Robot Artist
The number of different ways to span a thread between a larger number of hooks is astronomical.

Still Wondering If You'd Work For A Robot Boss?
'This is all coming to you courtesy of the simstim unit wired into your deck, of course.'

World's First Autonomous Tram In Germany
What's it like for autonomous trams when they're turned off at night?

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.