 |
Nanobees Sting Tumors With Melittin
Nanobees are nanoparticles laden with melittin, an ingredient in bee venom. Melittin is known to have therapeutic uses, but its use in medicine has been minimal due to the fact that it does damage to healthy cells as well. Researchers at Washington University in St. Louis came up with the nanobee idea as a way to get melittin directly to tumor cells.
(Nanobees with melittin sting cancer cells)
Among Dr. Soman's first experiments was to see how melittin interacted with the nanoparticles. He found that not only did it attach quickly to the outer, lipid layer of the nanoparticles, but that the attachment was stable, suggesting that the nanoparticle-melittin combination, or nanobee, might be able to circulate in the body and not attack healthy cells.The next issue was to figure out how to get the melittin, once it came upon a tumor, to detach from the nanoparticle and transfer to the cancer cells, taking its cell-killing properties with it. The researchers accomplished this by attaching a third component to the mix—a ligand, which is a chemical that binds two distinct compounds. The ligand they used in this case—which Dr. Schlesinger likens to a "molecular ZIP Code"—has an affinity for attaching to a receptor plentiful in newly formed blood vessels. That's useful in cancer treatment because tumors tend to form new blood vessels to feed themselves and grow.
In tests with mice, the nanobees slowed the growth of breast-cancer tumors significantly, shrank melanoma tumors and reduced precancerous lesions (compared with control groups).
These "nanobees" are yet another effort to find a way to deliver a measured quantity of agent to a very particular place in the body. When science fiction writers think about it, one way to solve this problem is to make a person very small. As in the sf classic Fantastic Voyage.
(Proteus from Fantastic Voyage)
Scroll down for more stories in the same category. (Story submitted 10/3/2009)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 0 )
Related News Stories - (" Medical ")
Spray-On Skin For Burns From ReCell Kit
Spray-on skin prepared from a patient's own skin cells may be the perfect choice for even severe second-degree burns.
Gregory Benford On Artificial Biological Selection for Longevity
Benford, a physics professor and sf writer, has put his money where Robert Heinlein's mouth was, and created a corporation to extend human life.
Your Thoughts On Youtube?
Scientists pull information out of the brains of people watching Youtube. Make up your own joke, but this method seems to work.
Death Algorithm Developed In Japan
Interesting work raises moral questions; I wonder if this algorithm will me made available in a simple home test.
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Current News
AirRobot Micro-UAV 'Fairies' In Shakespeare Play
At least they were not the 'rude mechanicals'.
Paralysis Ray Uses Photocontrolled Molecular Switch
Gerry was dubious. She had seen abortive attempts at paralysis rays before.
Brine Wells May Swallow Towns
Dissolve 1 teaspoon of the Quadraturin essence in 1 cup of water.
Will In-Vitro Meat Change Our Lives?
ChickieNobs, anyone?
Walky iPhone Finger Gesture Robot Controller
Let your fingers - uh - your robot do the walking. And hopping.
OnStar Stolen Vehicle Slowdown Foils Carjacker
Better than a car chase.
Robot Martial Arts Videos
Robo-Shiko!
Interactive TV Patent From Sony
Can you dance faster than the White Clown?
Smart Contact Lens With Power Harvesting Circuits
Smart contacts with VR connections.
'Significant Amount' Of Lunar Water Found
Droogs! There's water ice on the moon!
FOXP2 Tweak Yields Planet Of The Apes?
Get your filthy words off me, you damn dirty ape!
Lev, Theremin-Playing Robot
Patsy Cline classic played by robot.
XT-1 Micro Mouse With Blazing Speed
These are fully autonomouse robots.
Escape Pods, Refuge Of ISS Astronauts From Space Junk
Who first thought about escape pods?
Steerable Bowling Ball Is A Cheesy Spherical Robot
Once the province of geeks, now in bowling alleys.
Bio-Mechanics And Micro-Robotic Flight
Micro air vehicles and insect flight.
