Science Fiction
Dictionary
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 |
Fantastic Voyage Of Self-assembling Peptide Nanofibers
In the 1966 science fiction movie Fantastic Voyage, researchers miniaturize a delivery mechanism and inject it into a human body. In a modern day sequel, Harvard Medical School researchers have used injectable self-assembling peptide nanofibers loaded with the pro-survival factor PDGF-BB to protect rat hearts from injury and subsequent heart failure. Their study will appear in the January 2006 issue of the Journal of Clinical Investigation.
(1966 Fantastic Voyage)
Narrowed or blocked blood vessels are unable to deliver sufficient levels of oxygen to cardiomyocytes, which results in cardiomyocyte death, loss of the middle layer of the heart wall (the myocardium), and ultimately, heart failure. Therefore, therapies that protect cardiomyocytes from death may help prevent heart failure.In the current study, Richard Lee and colleagues show that PDGF-BB has a direct pro-survival effect on cardiomyocytes. The authors went on to design a strategy in which short, self-assembling peptide nanofibers bind this pro-survival growth factor and, following injection into rat myocardium, facilitated prolonged and controlled delivery of PDGF-BB to the infarcted heart for up to 14 days. This strategy protected cardiomyocytes from injury, reduced infarct size, and preserved cardiac function. This effect could not be achieved by injecting nanofibers or PDGF-BB alone.
In a previous paper, Dr. Lee and his team demonstrated that self-assembling peptide nanofibers can be injected, and that the resulting nanofiber microenvironment can be seen.
If you are interested in this topic, you might also be interested in an Artist's View Of Medical Nanorobots. Read more at ZDNet, the press release, and Molecular Cardiology. And thanks to Fred Kiesche for pointing this one out.
Scroll down for more stories in the same category. (Story submitted 12/20/2005)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 0 )
Related News Stories - (" Medical ")
MouthPad Supports Head And Tongue Tracking
'The operation that had transformed half his body... had located the control switchboard in his teeth.'- Alfred Bester, 1956.
Drug Induces Hibernation-Like State In Humans
'... drugged and chilled and stowed in sleep tanks.' - Robert Heinlein, 1951.
Drug To Regenerate Teeth In Humans
'We want to do something to help those who are suffering from tooth loss or absence,' said lead researcher Katsu Takahashi.
Illustrating Classic Heinlein With AI
'Stasis, cold sleep, hibernation, hypothermia, reduced metabolism, call it what you will - the logistics-medicine research teams had found a way to stack people like cordwood and use them when needed.' - Robert Heinlein, 1956
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Science Fiction
Timeline
1600-1899
1900-1939
1940's 1950's
1960's 1970's
1980's 1990's
2000's 2010's
Current News
Finally, Robot Conductors On Autonomous Buses
'Wardour Street,' he told the robot-conductor.'
RoboShiko! Sumo Exercises Still Good For Robots
'... the expressionless face before me was therefore that of the golem-wrestler, Rolem, a creature that could be set for five times the strength of a human being.'
Giant Robotic Hands At Gundam Next Future Science
'Waldo put his arms into the primary pair before him; all three pairs, including the secondary pair mounted before the machine, came to life.'
JWST Finds Bucking Centaur 29P/Schwassmann-Wachmann 1
'... the glittering little rocket bolted to the black iron behind him.'
BeamBike Solar Power Canopy For Electric Bikes
'The slender stalks of a sunshade-photocell collector...'
California Fireman Arrested For Starting Fires
'Fire is bright and fire is clean.'
Robots Need A Better Sense Of Touch
'First, it rubbed my arms...'
MouthPad Supports Head And Tongue Tracking
'The operation that had transformed half his body... had located the control switchboard in his teeth.'
REALLY Remote Control Excavators
'It takes over a second for the signal to get to the Moon...'
Disney Helping Robots Dance
Dance, Robots, Dance.
Kolors Virtual-Try-On Predicted, And TRIED, By Harry Harrison
'Bill blinked at his own face under the plumed helmet...'
Detecting Drones In Ukraine With Candy (Sukork)
'...a robot detector circuit closed, activating a bell."
Nevada Will Use AI To Decide Worker Benefits
'They had screwed up and been blacklisted by Manna.'
Tether Cryptocurrency Flow Rate US$190Bn Per Day
'Alex did not find it surprising that people... were electronically minting their own cash.'
First Trips To Mars Announced By Elon Musk
'I had determined that my first attempt should be a visit to Mars.'
WaPOCHI Micro-Mobility Robot Follows Like A Pet With Your Bags
To follow the user like a pet while carrying their cargo!
