Science Fiction Dictionary
A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

 

Limb Regeneration Grows Closer

How does limb regeneration work in animals like salamanders? If you cut off their tails, they are able to completely recreate the missing limb, including bones, muscle, skin, blood vessels and nerves.

In salamanders, new tissues come from a tumorlike mass of cells that forms at the site of the injury, called the blastema. Until now, most scientists thought that the blastema contained a population of stem cells that had become pluripotent--capable of giving rise to all the needed tissues.

However, new research published in Nature seems to indicate that the mechanism is simpler than previously supposed. An experiment designed by Elly Tanaka at the Center for Regenerative Therapies, in Dresden, Germany employed a new method for tracking what happens in the axolotl when it is injured.


( Schwann cells are shown here in a salamander limb )

The researchers first created transgenic axolotls that carried green fluorescent protein (GFP) in their entire bodies. When the animals were still embryos, the researchers removed a piece of tissue from the limb region of the transgenic animals and transplanted the tissue into the same location in nontransgenic axolotls. The transplants were incorporated into the growing body as normal cells, and when the limb of the transplant recipients were then severed, the researchers could track the fate of the fluorescent cells as the limb regrew.

The researchers used this method to track the fate of cells of the inner and outer skin, muscles, and cartilage, as well as Schwann cells, which insulate nerve fibers. They found that, contrary to previous evidence, muscle cells at the amputation site only become muscle cells in the new limb. Other cell types also stuck to their previous identities; the only exception, Tanaka says, is that cells of the inner layers of skin and cartilage seem to be able to transform into one another.

Frank Herbert wrote about the idea of limb regeneration in his appropriately named "axolotl tank" from his 1969 novel Dune Messiah:

"Even in defeat," Edric said, "your father's Sardaukar did not abandon wisdom. Let us suppose a wise Sardaukar commander recognized the swordmaster in a corpse his men had slain. What then? There exist uses for such flesh and training . . . if one acts swiftly..."

"A Tleilaxu ghola," Irulan whispered...

...Edric said. "...let us assume that our wise Sardaukar commander had Idaho's corpse preserved for the axolotl tanks.
(Read more about Herbert's axolotl tank)

From MIT's Technology Review.

Scroll down for more stories in the same category. (Story submitted 7/3/2009)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 5 )

Related News Stories - (" Medical ")

Prototype 3D Printer Could Print Arteries In Seconds
'... in the tank the new body and the new mind and memory and life has taken almost instant form.' - Clifford Simak, 1963.

NextSense Earbuds Spy On Your Brain
'Your cephalochromoscope that cost you nine hundred dollars... colors and ceph patterns...' - Philip K. Dick, 1977.

Do Contagious Vaccines Work Better?
'...suppose we do plant an epidemic of Nine-Day Fever in Zone Red.' - Robert Heinlein, 1952.

Artificial, Implantable Kidney Prototype
'George Walt's corporate existence proved the workability of wholly mechanical organs...' - Philip K. Dick, 1964.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

Science Fiction Timeline
1600-1899
1900-1939
1940's   1950's
1960's   1970's
1980's   1990's
2000's   2010's

Current News

NAVER Labs Haptic Device 2.0 Robot vs. IKEA
'... the two pairs of waldoes in the screen followed in exact, simultaneous parallelism.'

Spaceships Should Last So Long
'THE SPACE VESSEL was traveling swiftly… For over five thousand years they had Voyaged on and on.’

Shine On, Portable Wind Turbine
'Sometimes a man has a windmill on his roof...'

Amazing Indoor Robotic Drones Mimic Dolphins and Whales
'They circled the vast audiences, dancing, twittering, chirping...'

Space Station Shutters
'The sun-quilt was a patchwork of colors and materials on the inward side, but silvered on the outward side...'

Tiny Mining - Extract Precious Industrial Minerals From Your Own Body
'Jim, I saw them reduce four of my doctors and nurses into those little cubes!'

MIT Proposes Space Bubbles To Combat Climate Change, Misses The Point Of Space Bubbles
'Fats Jordan was hanging in the center of the Big Glass Balloon, hugging his guitar to his massive black belly above his purple shorts..'

Tianjin Solar Vehicle From Hanergy (2022) Looking Like Heinlein's (1940)
'When confronted by hills, or rough terrain, it did not stop, but simply slowed until the task demanded equaled its steady power output.'

Study Reveals Effect Of Space Travel On The Brain
'... the brain is no longer subjected to the accustomed pull, and it expands slightly in all directions.'

Sky Cruise Nuclear Powered Flying Hotel Concept
'... the huge air-freighter Jupiter.'

The Mojo Smart Contact Lens Experience
'... the lens displays would be useless without a wearable computer to do the graphics.'

Small Town Wants 60 License Plate Readers
'the registration number which the traffic control automatically photographed as she left the controlway...'

Lightyear 0 World's First Production-Ready Solar Car
'It could maintain a steady six miles per hour...'

AI Robots Excel At Trash Sorting And Recycling
'Then they press one of these here thirteen buttons...'

Could Increased Space Rocketry Damage The Ozone Layer?
'...without burning a single hydrocarbon molecule to injure the diseased atmosphere any further.'

Dyson's Secret Household Robots
'...work a human being does around a house.'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.