The Secret of Longevity?

Apparently, genes, according to scientists at Stanford University and the University of Bologna.

Genetic studies so far have only identified a single gene (APOE, known to be involved in Alzheimer’s disease) that is different in centenarians versus normal agers.

To find the additional longevity genes, the authors first developed a new statistical method called informed GWAS (genome-wide association studies), which uses knowledge from 14 diseases to narrow down the search genes associated with longevity.

Using iGWAS, the scientists found eight SNPs (single nucleotide polymorphisms — molecular variations at different locations on the gene) that are significant for the centenarians they studied, and they were able to validate four of these in replication studies of long-lived subjects.

The four “longevity loci” (gene locations) along with the APOE gene may provide clues about physiological mechanisms for successful aging. These loci are known to be involved in various processes including cell senescence, autoimmunity, and cell signaling, and also with Alzheimer’s disease.

Future work may lead to a better understanding of how these genes promote successful aging and could identify additional longevity genes by recruiting more centenarians for analysis.

Robert Heinlein came to pretty much the same conclusion in his 1941 classic Methuselah's Children, in which he introduces his Howard Families, the long-lived.

"The first offspring resulting from unions assisted by the Howard Foundation were born in 1875. They aroused no comment, for they were in no way remarkable. The Foundation was an openlychartered non-profit corporation--"

On March 17, 1874, Ira Johnson, medical student, sat in the law offices of Deems, Wingate, Alden, & Deems and listened to an unusual proposition. At last he interrupted the senior partner. "Just a moment! Do I understand that you are trying to hire me to marry one of these women?"
The lawyer looked shocked. "Please, Mr. Johnson. Not at all"
"Well, it certainly sounded like it."
"No, no, such a contract would be void, against public policy. We are simply informing you, as administrators of a trust, that should it come about that you do marry one of the young ladies on this list it would then be our pleasant duty to endow each child of such a union according to the scale here set forth. But there would be no Contract with us involved, nor is there any 'proposition' being made to youand we certainly do not urge any course of action on you. We are simply informing you of certain facts."
Ira Johnson scowled and shuffled his feet. "What's it all about? Why?"
"That is the business of the Foundation. One might put it that we approve of your grandparents."
"Have you discussed me with them?" Johnson said sharply.
He felt no affection for his grandparents. A tight-fisted foursome-if any one of them had had the grace to die at a reasonable age he would not now be worried about money enough to finish medical school.

Via KurzweilAI.

Scroll down for more stories in the same category. (Story submitted 12/21/2015)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Medical ")

Biotech Firms Raised $Millions For Anti-Agathics (Longevity Drugs)
'Against Death doth no simple grow.' - James Blish, 1957.

Medical Tattoos Are STILL Being Researched
'Following the current craze, she has had a subdermal pattern of micro-channels implanted.'

Rise Of Skywalker Could Trigger Epileptic Seizures
'... then the screen started to flicker. I stared at it for a while.' - John Varley, 1984.

Injectable Magnetic Fluid Slows Bleeding, Aids Magneto
'There's something different about you.'

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Neural Net Discovers Antibiotic
'...instantly the TEMS was ... creating and discarding scores of new sciences.'

China Delivery Robot Development Quickens During COVID-2019 Outbreak
'Something very much like a camouflage-painted kangaroo.'

Via Virtual Reality, Mother Encounters Deceased Daughter
'But that barrier was going to melt away someday soon. The transhumanists had promised...'

Clothes That Do Photosynthesis
'Clothes are no longer made from dead fibers of fixed color and texture...'

Stratuscent Electronic Nose
'It's picking up diphenyl compounds and tetra hydrocarbons.'

CIMON Companion Robot For Space Station Astronauts
'... in some departments their power is absolute.'

Qbit Robot Bartender Also Makes Coffee
'...he sipped the cognac that the robot bartender handed him.'

Moving Desks Not SciFi After All
'Charged with hope, he zipped from stack to stack...'

Cruise Autonomous Car Drives Aimlessly For An Hour
Convincing video shows progress (and limitations).

Fast Charging A Bus In 20 Seconds
'... in almost every town and village.'

Realistic Translation With The Waverly Labs Ambassador
'The speech patterns you actually hear decode the brainwave matrix which has been fed into your mind by your Babel fish.'

Biotech Firms Raised $Millions For Anti-Agathics (Longevity Drugs)
'Against Death doth no simple grow.'

Out-Of-Work Blue Collar Robots Need Your Help
'His legs relaxed with a rattle as he cut off all power below his waist... and ran his eye down the Help Wanted - Robot column...'

The Dawn Of Orbiting Manufacturing In 2020?
'It can be mass-produced only in the orbiting factories.'

Smart Contact Lenses Charges With 3D Printed Antenna
'He realized that it was not quite a clear lens.'

Segway S-Pod Fulfills Dire 1928 SciFi Prophecy
'Noiselessly, on rubber-tired wheels, they journeyed down the long aisles...'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.