Science Fiction
Dictionary
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 |
The Secret of Longevity?
Apparently, genes, according to scientists at Stanford University and the University of Bologna.
To find the additional longevity genes, the authors first developed a new statistical method called informed GWAS (genome-wide association studies), which uses knowledge from 14 diseases to narrow down the search genes associated with longevity.
Using iGWAS, the scientists found eight SNPs (single nucleotide polymorphisms — molecular variations at different locations on the gene) that are significant for the centenarians they studied, and they were able to validate four of these in replication studies of long-lived subjects.
The four “longevity loci” (gene locations) along with the APOE gene may provide clues about physiological mechanisms for successful aging. These loci are known to be involved in various processes including cell senescence, autoimmunity, and cell signaling, and also with Alzheimer’s disease.
Future work may lead to a better understanding of how these genes promote successful aging and could identify additional longevity genes by recruiting more centenarians for analysis.
Robert Heinlein came to pretty much the same conclusion in his 1941 classic Methuselah's Children, in which he introduces his Howard Families, the long-lived.
On March 17, 1874, Ira Johnson, medical student, sat in the law offices of Deems, Wingate, Alden,
& Deems and listened to an unusual proposition. At last he interrupted the senior partner. "Just a
moment! Do I understand that you are trying to hire me to marry one of these women?"
Via KurzweilAI.
Genetic studies so far have only identified a single gene (APOE, known to be involved in Alzheimer’s disease) that is different in centenarians versus normal agers.
"The first offspring resulting from unions assisted by the Howard Foundation were born in 1875.
They aroused no comment, for they were in no way remarkable. The Foundation was an openlychartered
non-profit corporation--"
The lawyer looked shocked. "Please, Mr. Johnson. Not at all"
"Well, it certainly sounded like it."
"No, no, such a contract would be void, against public policy. We are simply informing you, as
administrators of a trust, that should it come about that you do marry one of the young ladies on this list
it would then be our pleasant duty to endow each child of such a union according to the scale here set
forth. But there would be no Contract with us involved, nor is there any 'proposition' being made to youand
we certainly do not urge any course of action on you. We are simply informing you of certain facts."
Ira Johnson scowled and shuffled his feet. "What's it all about? Why?"
"That is the business of the Foundation. One might put it that we approve of your grandparents."
"Have you discussed me with them?" Johnson said sharply.
He felt no affection for his grandparents. A tight-fisted foursome-if any one of them had had the
grace to die at a reasonable age he would not now be worried about money enough to finish medical
school.
Scroll down for more stories in the same category. (Story submitted 12/21/2015)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 0 )
Related News Stories - (" Medical ")
3D Printed Organs From Space
'For a while your colonists will have to come up to the [orbital] Hospital...'
Health Kiosk Has No Human Doctor
'The electronic body analyzer had been developed...' - Michael Crichton, 1969.
NEO Brain Computer Interface (BCI)
'The remains of the lace took on the rough shape of a brain...' - Iain Banks, 2010.
MIT Computerized Bionic Leg Is Part Of The User
'The leg was to function, in a way, as a servo-mechanism operated by Larry’s brain, through the mediation of the electronic brain in the leg.' - Charles Recour, 1949.
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Science Fiction
Timeline
1600-1899
1900-1939
1940's 1950's
1960's 1970's
1980's 1990's
2000's 2010's
Current News
Birds Learn To Sing Pictures ala Frank Herbert's Distrans
'We will fight in the time of fighting.'
ElectionSim: China's 'Ender's Game' Battle Sim, Or Lem's 'Kingdom In A Box'?
'So, Ender, we will now begin your education.'
Tactile Skin Supplier Map
'What strange sensitivity! What an amazing development of science was manifested in every move and act and word of this Robot!'
Flock Stymied By 'Adversarial Fashion'
'Forget the head atop it, the legs below, feet, arms, hands. It compels erasure.'
Orb Nomad Zero-Emission Electric Aircraft
'That explains how it was so easy for me to remain motionless in midair or to perch on a flagpole in imitation of a giant bird, even in the windy city of Chicago.'
ICE Buys Shock Gloves Like Batman's
What else is the Caped Crusader using?
Factories In The Sky Will Surpass Those Of Earth
'The thirty-odd miles of The Factory’s circumference...'
Sleeper Drones Lie in Wait
'Wandering mines, you took them out on the edge of the desert, set them down and activated them.'
Warfare Goes Underground In Ukraine
'Once in the very first weeks of the war, before everyone had been evacuated from the surface...'
3D Printed Organs From Space
'For a while your colonists will have to come up to the [orbital] Hospital...'
Robot Bees 3D Printed By Festo
'At first I was struck by the large size of these bees..'
DIY Robot Scorpion Crushes It
'...it raised its front end off the ground and waved its antennae at them, then raised one armoured claw as if to snip them out of the sky.'
How To Settle An Argument Between Two Robots
'Henry... assumed the curious absent look of a robot talking on the TBR circuits.'
The Wind Phone Calls Those Who Have Passed On
'Only I heard that!'
Don't Want To Wear A TIght Shiny Bodysuit?
'He looked a good bit like an elderly, fat beetle.'
Light Society: Simulates Earth-Scale Society With A Billion AI Agents
'The king, an old hand in the running of tyrannies, instantly grasped the directions...'
