Gene-Edited Muscle Dogs From China

Gene editing has been used for the first time to produce customized dogs; Chinese researchers have created beagles with double the muscle mass by deleting a gene called myostatin.


(China's gene-edited muscle dogs)

The dogs have “more muscles and are expected to have stronger running ability, which is good for hunting, police (military) applications,” Liangxue Lai, a researcher with the Key Laboratory of Regenerative Biology at the Guangzhou Institutes of Biomedicine and Health, said in an e-mail.

Lai and 28 colleagues reported their results last week in the Journal of Molecular Cell Biology, saying they intend to create dogs with other DNA mutations, including ones that mimic human diseases such as Parkinson’s and muscular dystrophy, in order to test drugs and other treatments. “The goal of the research is to explore an approach to the generation of new disease dog models for biomedical research,” says Lai. “Dogs are very close to humans in terms of metabolic, physiological, and anatomical characteristics.”

The Chinese beagle project was led by Lai and Gao Xiang, a specialist in genetic engineering of mice at Nanjing University. The dogs are being kept at the Guangzhou General Pharmaceutical Research Institute, which says on its website that it breeds more than 2,000 beagles a year for research. Beagles are commonly used in biomedical research in both China and the U.S.

Genome editing refers to newly developed techniques that let scientists easily disable genes or rearrange their DNA letters.

SF fans may recall the modded dogs in John Brunner's 1976 novel Shockwave Rider; they were genetically modified for higher intelligence, and were used to sniff out people who lie or use undesirable substances based on their body odor.

...something moved, emerging from shadow beside the workbench. A dog. A vast, slow-moving graceful dog whose ancestry might have included Great Dane, Irish wolfhound, possibly Husky or Chinook... plus something else, something strange, for its skull was improbably high-domed and its eyes, deep-set, were disturbingly uncanine.

"No need to be alarmed," the man rumbled... "Never met a dog like this before? You're in for an educational experience.

From Technology Review.

Scroll down for more stories in the same category. (Story submitted 10/15/2015)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Biology ")

Mini-Brains In A Dish
'Cultured brains on a slab.' - Peter Watts, 1999.

NASA's Prototype Lunar Greenhouse For Mars And Moon
'In contrast to the airless desolation outside, the interior of this five-acre greenhouse was the one most desirable place to be.' - Raymond Z. Gallun, 1951.

Researchers Say 'Biohybrid Robot' - Clarke Said 'Biot'
'... The biological robots were not living creatures.' - Arthur C. Clarke, 1972.

Unique DNA To Foil Parts Counterfeiters
'... the only molecule, a unique protein amino acid, which could not be duplicated.' - Philip K. Dick, 1965.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Bat Bot Robotic Flapping-Wing Drone
'The dark birdforms dotted the mountaintops like statues of prehistoric beasts, wings outspread...'

NASA's Astronaut Rescue Ball
'Ball and closely-prisoned man plummeted downward..'

ARM Wants To Build Brain Chips
'Slivers of microsoft, angular fragments of colored silicon...'

Sky Fence - A Drone-Proof Shield Created Over Prison
'There’s still a protective field over the whole thing. It volatilizes anything that tries to get through.'

Geoengineering The Atmosphere For Climate Change
'...a uniform temperature for each degree of latitude the year round.'

Archinaut Orbiting Robotic Factory
'mass-produced only in the orbiting factories...'

Cryonic Preservation - The Last Perk You'll Ever Need
'Is there not also a law providing for voluntary suspension of animation?'

Computers Understand Humans By Watching And Modeling Them
Soon, your computer will be watching you... and judging you.

NASA Asks For Moon To Earth Delivery Ideas
'Authority's 3-g catapult was almost one hundred kilometers long...'

Musk Tunnels Wisely Restrict Drivers
Too many robots.

Robot Swarms Controlled With Augmented Reality
'You're not thinking in enough dimensions...'

MIT's C-LEARN Helps Robots Transfer Learning To Other Robots
'Talk Between Robots radio...'

Mini-Brains In A Dish
'Cultured brains on a slab.'

Rapid Automated Search For Habitable Planets Needed
'I was near enough it now to set my automatic astronomical instruments to searching it for a habitable planet.'

WatchSense Perfect For Fat-Fingered Smartwatch Owners
'Now all you had to do was wave your hand in the general direction of the components...'

Digital Construction Platform Robot 3D Prints A Building
'It extrudes material like a spider.'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.