Gene-Edited Muscle Dogs From China

Gene editing has been used for the first time to produce customized dogs; Chinese researchers have created beagles with double the muscle mass by deleting a gene called myostatin.


(China's gene-edited muscle dogs)

The dogs have “more muscles and are expected to have stronger running ability, which is good for hunting, police (military) applications,” Liangxue Lai, a researcher with the Key Laboratory of Regenerative Biology at the Guangzhou Institutes of Biomedicine and Health, said in an e-mail.

Lai and 28 colleagues reported their results last week in the Journal of Molecular Cell Biology, saying they intend to create dogs with other DNA mutations, including ones that mimic human diseases such as Parkinson’s and muscular dystrophy, in order to test drugs and other treatments. “The goal of the research is to explore an approach to the generation of new disease dog models for biomedical research,” says Lai. “Dogs are very close to humans in terms of metabolic, physiological, and anatomical characteristics.”

The Chinese beagle project was led by Lai and Gao Xiang, a specialist in genetic engineering of mice at Nanjing University. The dogs are being kept at the Guangzhou General Pharmaceutical Research Institute, which says on its website that it breeds more than 2,000 beagles a year for research. Beagles are commonly used in biomedical research in both China and the U.S.

Genome editing refers to newly developed techniques that let scientists easily disable genes or rearrange their DNA letters.

SF fans may recall the modded dogs in John Brunner's 1976 novel Shockwave Rider; they were genetically modified for higher intelligence, and were used to sniff out people who lie or use undesirable substances based on their body odor.

...something moved, emerging from shadow beside the workbench. A dog. A vast, slow-moving graceful dog whose ancestry might have included Great Dane, Irish wolfhound, possibly Husky or Chinook... plus something else, something strange, for its skull was improbably high-domed and its eyes, deep-set, were disturbingly uncanine.

"No need to be alarmed," the man rumbled... "Never met a dog like this before? You're in for an educational experience.

From Technology Review.

Scroll down for more stories in the same category. (Story submitted 10/15/2015)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Biology ")

Monkey Gets A Bigger Brain, Thanks To Human Gene
'It's a madhouse! a madhouse!' - Planet of the Apes, 1968.

Mushroom Coffin Returns You To Nature, Naturally
'She touched the leaf. She was wanted.' - Philip K Dick, 1954.

Mechanical Milking Of Microalgae For Fuel Production
'They call 'em culture tanks. They have bugs -- germs -- growing in them.' - Hal Clement, 1950.

Fetal Lamb Rests In Artificial Womb
'... stewing warm on their cushion of peritoneum and gorged with blood-surrogate and hormones, the foetuses grew and grew...' - Aldous Huxley, 1932.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Las Vegas Tunnels To Have Autonomous Teslas
'...just a steady velvety whirr as the taxi sped along.'

TCL CSOT 17-Inch Printed OLED Scrolling Display
'..a wide sheet of clear material suddenly flared with light and swirling colour.'

Reachy Humanoid VR Teleoperation App
"I went to the control room where the three other men were manipulating their mechanical men...'

Unitree A1 Robot ala Black Mirror and Snow Crash
'The legs are long, curled way up to deliver power...'

DALL-E Makes Creative Images From Text
Okay, sf fans. If you could have some art created from a science fiction sentence, what sentence would you pick?

BladeBUG Robots Clean Massive Wind Turbine Blades
'There were the cleaners, with large padded feet, who were apparently polishing their way the whole length...'

Looms To Manually Weave Lunar Rover Wheels
It's fascinating to me how the Apollo program forced people to think outside their usual boxes.

IceBot Antarctic (Planetary?) Robotic Explorers Made Of Ice
'Some will combine in place to form more complicated structures, like excavators or centipedes.'

Glad 2020 Is Over
Maybe you missed one of these?

PEDOT Polymer Could Enhance Brain-Machine Interfaces
'the hair-fine wire going deep into Owen's brain, down into the pleasure center.'

Study: Robots Encourage Humans To Take Risks
Not exactly Three Laws compliant.

Kinetic Buildings And Psychotropic Houses
'There was a dim whirring, and the spheres tipped and began to rotate...'

Jupe Urban Escape Pods Have Tesla, SpaceX Roots
'The houses are prefabricated units... and they sell at the flat rate of five hundred dollars a room — set up.'

Best Robot Dance Video Of 2020
'I can Mashed Potato... I can do the Twist.'

Vertical Farm In Singapore's Output Is 1.5 Tons Per Day
'A towering eighty-story structure like the office "In-and-Out" baskets stacked up to the sky.'

3D Printed 'Blisk' Manufactured In Orbit
'It can be mass-produced only in the orbiting factories...'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.