In Vivo Micromotors Powered By Stomach Acid

Check out this cool micromotor that is powered by the gastric acid in a living mouse stomach; it was developed by researchers from the Department of Nanoengineering, University of California, San Diego, La Jolla, California.


(Artificial Micromotors in the Mouse’s Stomach)

Artificial micromotors, operating on locally supplied fuels and performing complex tasks, offer great potential for diverse biomedical applications, including autonomous delivery and release of therapeutic payloads and cell manipulation. Various types of synthetic motors, utilizing different propulsion mechanisms, have been fabricated to operate in biological matrices.

However, the performance of these man-made motors has been tested exclusively under in vitro conditions (outside the body); their behavior and functionalities in an in vivo environment (inside the body) remain unknown. Herein, we report an in vivo study of artificial micromotors in a living organism using a mouse model. Such in vivo evaluation examines the distribution, retention, cargo delivery, and acute toxicity profile of synthetic motors in mouse stomach via oral administration.

Using zinc-based micromotors as a model, we demonstrate that the acid-driven propulsion in the stomach effectively enhances the binding and retention of the motors as well as of cargo payloads on the stomach wall. The body of the motors gradually dissolves in the gastric acid, autonomously releasing their carried payloads, leaving nothing toxic behind.

This work is anticipated to significantly advance the emerging field of nano/micromotors and to open the door to in vivo evaluation and clinical applications of these synthetic motors.

If we're ever going to get the Proteus from the 1966 novel Fantastic Voyage, we're going to need to get that source of motive power working. This working micromotor powered by stomach acid looks like a good start.


(Fantastic Voyage trailer)

Via Artificial Micromotors in the Mouse’s Stomach: A Step toward in Vivo Use of Synthetic Motors.

Scroll down for more stories in the same category. (Story submitted 1/20/2015)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Medical ")

Beat Covid-19 With AIR By MicroClimate - At Last I Get My PAPR
More than just a bubble.

EPR Is Quick, Temporary Biostasis
'The cold-pack was being sucked out greedily by plastic suction tendrils...' - Philip K. Dick, 1960.

TytoCare Offers Futuristic Home Care
'Immediately an enormous apparatus fell on to her out of the ceiling...' - EM Forster, 1909.

Would You Swallow An Origami Robot?
'Swallow it in an emergency--it goes down easily and works just as well inside as outside.' - Doc Smith, 1934.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

OK, NASA 3D Printer Of Food Not Yet Star Trek Food Synthesizer
Maybe not, but we're seeing definite progress.

Kelly Clarkson Show Like Black Mirror '15 Million Merits'
'These people are pieces of software called avatars.'

Salto Jumping Robot Now Sticks Landing!
'Lucky touched the leap knob and the hopper's leg retracted.'

Gyroscopic Median-Straddling Mass Transit Vehicles
'It was among these leviathans that the little gyrocar was daring to thrust its puny self...'

Bigrating Laser Beam-Riding Light Sail Is Self-Correcting
'That sail will be twenty thousand miles at the wide part.'

ISS Astronauts Test Estee Lauder 'Advanced Night Repair' Skin Serum
'Out in the New Moon, just ask for what you want...'

LG Wing Twisting Smartphone Might Be Fun
'A polycarbon screen unfurled...'

Mushroom Coffin Returns You To Nature, Naturally
'She touched the leaf. She was wanted.'

Will ATT Offer Ad-Subsidized Cellphone Service
'For long-distance calls the ratio of commercial to conversation was as high as 10 to 1...'

Gyro-X Self-Balancing Two-Wheeler Car
'Indeed, the gyrocar was a sight to make a man look twice.'

Beat Covid-19 With AIR By MicroClimate - At Last I Get My PAPR
More than just a bubble.

Mi TV LUX Transparent Edition OLED TV
The Look of Things To Come.

Metalenses Now Reconfigurable With Liquid Crystal
'Hufhuf oil held in static tension...'

'Alexa For Residential' A Landlord's Dream (Tenant's Nightmare?)
'...unseen mechanical entities... that are in our very midst. One of them following each of us.'

Gather Ye Moonrocks While Ye May
'The law of filing on newly discovered asteroids was definite.'

InMotion V11 Electric Unicycle Gets Air (Video)
'A tumblebug does not give a man dignity...'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.