Spray-On Polymer Mats Heal Wounds Fast

Researchers have discovered that they can spray polymer nanofibers directly onto living tissues using an airbrush purchasable at any hardware store. These biodegradable mats of sticky fibers can seal surgical incisions and help them to heal.


(From PLGA nanofibers sprayed onto gloved hand)

Current methods for making the mats—such as electrospinning, which involves electric current—would damage living cells if the mats were made in situ. To devise a way to create the mats directly on the tissue, Kofinas and colleagues adapted a commercial airbrush, a tool more commonly used to apply paint.

They tinkered with different formulations of a biodegradable polymer, poly(lactic-co-glycolic acid), or PLGA, to find one that would work in the airbrush. By choosing a particular molecular weight of PLGA and concentration of acetone as the solvent, they could control the diameter of the resulting fibers. They ended up producing mats with fiber diameters of about 370 nm.

The researchers showed that the mats could seal diaphragm hernias and cuts to the lung, intestine, and liver in a pig. The acetone appears to evaporate before the nanofibers get deposited, suggesting that the solvent won’t pose toxicity problems, according to the paper. Cells sprayed with the PLGA nanofibers show no change in health after 24 hours. In lab tests, the nanofiber mats degraded completely over a 42-day period.

The polymer nanofiber mats are currently being improved and studied for upcoming surgical trials in laboratory animals.

Science fiction fans have been nursing their cuts and scrapes ever since the 1960 novel Dr. Futurity, in which Philip K. Dick wrote about art-derm - spray-on skin that could be directly applied to wounds.

Over her lacerated right shoulder he sprayed art-derm; it sealed off the open wound, halted bleeding, and prohibited infection.
(Read more about art-derm)

From In Situ Deposition of PLGA Nanofibers via Solution Blow Spinning via Chemical & Engineering News.

Scroll down for more stories in the same category. (Story submitted 3/27/2014)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Medical ")

You'll Regrow That Limb, One Day
'... forcing the energy transfer which allowed him to regrow his lost fingers.' - Frank Herbert, 1972.

First 3D Printed Human Corneas From Stem Cells
Just what we need! Lots of spare parts.

Nanorobots Roam Your Bloodstream, Cleaning It
Too bad they won't have lasers, though...

MIT Ampli Blocks Build Biomedical Devices
Damn it Spock, I'm a doctor not an engineer!

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Las Vegas Humans Ready To Strike Over Robots
'A worker replaced by a nubot... had to be compensated.'

You'll Regrow That Limb, One Day
'... forcing the energy transfer which allowed him to regrow his lost fingers.'

Elon Musk Seeks To Create 1941 Heinlein Speedster
'The car surged and lifted, clearing its top by a negligible margin.'

Somnox Sleep Robot - Your Sleepytime Cuddlebot
Science fiction authors are serious about sleep, too.

Real-Life Macau or Ghost In The Shell
Art imitates life imitates art.

Has Climate Change Already Been Solved By Aliens?
'I had explained," said Nessus, "that our civilisation was dying in its own waste heat.'

First 3D Printed Human Corneas From Stem Cells
Just what we need! Lots of spare parts.

VirtualHome: Teaching Robots To Do Chores Around The House
'Just what did I want Flexible Frank to do? - any work a human being does around a house.'

Messaging Extraterrestrial Intelligence (METI) Workshop
SF writers have thought about this since the 19th century.

Nanorobots Roam Your Bloodstream, Cleaning It
Too bad they won't have lasers, though...

Galini 3D Printed Sleeping Pod Tiny Houses
'The houses are prefabricated units...'

MIT Boffins Create Psychopath AI On Purpose
There's a lesson in this for neural net AI engineers everywhere.

Skin Electronics 3D Printed
'June's body is a tracery of lambent lines, like some arcane capillary circuitry...'

Artificial Sensory Neurons For Prosthetics, Robots
Great for humans and robots!

China Uses Artificial Intelligence To Grade Student Papers
Looks like the City Fathers are starting to take over China's education system.

Electronic Tongues Will Rule The Kitchen
'Install taste buds in the end of one tentacle...'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.