Spray-On Polymer Mats Heal Wounds Fast
Researchers have discovered that they can spray polymer nanofibers directly onto living tissues using an airbrush purchasable at any hardware store. These biodegradable mats of sticky fibers can seal surgical incisions and help them to heal.
(From PLGA nanofibers sprayed onto gloved hand)
Current methods for making the mats—such as electrospinning, which involves electric current—would damage living cells if the mats were made in situ. To devise a way to create the mats directly on the tissue, Kofinas and colleagues adapted a commercial airbrush, a tool more commonly used to apply paint.
They tinkered with different formulations of a biodegradable polymer, poly(lactic-co-glycolic acid), or PLGA, to find one that would work in the airbrush. By choosing a particular molecular weight of PLGA and concentration of acetone as the solvent, they could control the diameter of the resulting fibers. They ended up producing mats with fiber diameters of about 370 nm.
The researchers showed that the mats could seal diaphragm hernias and cuts to the lung, intestine, and liver in a pig. The acetone appears to evaporate before the nanofibers get deposited, suggesting that the solvent won’t pose toxicity problems, according to the paper. Cells sprayed with the PLGA nanofibers show no change in health after 24 hours. In lab tests, the nanofiber mats degraded completely over a 42-day period.
The polymer nanofiber mats are currently being improved and studied for upcoming surgical trials in laboratory animals.
Science fiction fans have been nursing their cuts and scrapes ever since the 1960 novel Dr. Futurity, in which Philip K. Dick wrote about art-derm - spray-on skin that could be directly applied to wounds.
Over her lacerated right shoulder he sprayed art-derm; it sealed off the open wound, halted bleeding, and prohibited infection.
(Read more about art-derm)
From In Situ Deposition of PLGA Nanofibers via Solution Blow Spinning via Chemical & Engineering News.
Scroll down for more stories in the same category. (Story submitted 3/27/2014)
Follow this kind of news @Technovelgy.
| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
you like to contribute a story tip?
Get the URL of the story, and the related sf author, and add
Comment/Join discussion ( 0 )
Related News Stories -
Mind-Altering Drugs Administered Deep Into The Brain
'Happy to serve!'- Greg Bear, 2015.
BRUISE Smart Injury Detection Suit
'... Bee could see that three of them were disabled and two of them damaged.' - Orson Scott Card, 1985.
First US Clinical Trial For Wearable Artificial Kidney
'Wholly mechanical organs...' - Philip K. Dick, 1964.
Open Bionics To Produce Deus Ex Prosthetic Designs
Be a part of a science fictional future.
Technovelgy (that's tech-novel-gee!)
is devoted to the creative science inventions and ideas of sf authors. Look for
the Invention Category that interests
you, the Glossary, the Invention
Timeline, or see what's New.
Will There Be A Digital Afterlife?
'A quick exchange of energies resulting from the relocation of discorporate states.'
ROCKY - Resistive Overload Combined With Kinetic Yo-Yo
'Joe got out the gravity-simulator harnesses..'
China Bans Self-Driving Car Testing
Innovation hits some bumps.
Robotic Lawnmower Fulfills SciFi Homeowner's Dreams
'The mower reached the edge of the lawn, clucked to itself like a contented hen...'
7-Eleven Drone Delivers Chix Sandwich And Slurpee
'It was a smooth ovoid floating a few inches from the floor...'
Beta-Ti3Au Titanium-Gold Alloy Hardest Tissue-Compatible Metal
It needs a more science-fictional name!
Solar Plane Circles The Globe
'Tropism-like pursuit of the sun across the sky as they recharged their batteries...'
Audiobooks - Fastest Growing Format In Publishing
'The public preferred lectons...'
SuperMeat - Crowdfunding Pohl/Kornbluth's Chicken Little
'Chicken Little, who would be sliced and packed to feed people from Baffinland to Little America.'
Martian-Grown Food Might Be Fine
'I don’t want to come off as arrogant here, but I’m the best botanist on the planet.'
MARLO Robot Attempts Wave Field
'It is apparent that he will walk before his human brother.'
3RDiTEK Lifeblogging Headband Camera
'It's logging anyway - everything you see on duty goes into the black box.'
3D-Printed Biohybrid Is A Tissue-Engineered Robot
'The directing neurological tissue that forms the basis of the swibble is alive...'
Steerable Locusts Detect Explosives
Science fiction writers again provide a blueprint for the future.
No Human Drivers By 2040 - Israel
'It's been a criminal offense,,, to drive manually on a public highway.'
Graphene Ultracapacitor Airships For Heavy Lifting
'The war-balloons were to be kept for purposes of transportation of heavy articles...'
More SF in the News Stories
More Beyond Technovelgy science news stories