Spray-On Polymer Mats Heal Wounds Fast

Researchers have discovered that they can spray polymer nanofibers directly onto living tissues using an airbrush purchasable at any hardware store. These biodegradable mats of sticky fibers can seal surgical incisions and help them to heal.


(From PLGA nanofibers sprayed onto gloved hand)

Current methods for making the mats—such as electrospinning, which involves electric current—would damage living cells if the mats were made in situ. To devise a way to create the mats directly on the tissue, Kofinas and colleagues adapted a commercial airbrush, a tool more commonly used to apply paint.

They tinkered with different formulations of a biodegradable polymer, poly(lactic-co-glycolic acid), or PLGA, to find one that would work in the airbrush. By choosing a particular molecular weight of PLGA and concentration of acetone as the solvent, they could control the diameter of the resulting fibers. They ended up producing mats with fiber diameters of about 370 nm.

The researchers showed that the mats could seal diaphragm hernias and cuts to the lung, intestine, and liver in a pig. The acetone appears to evaporate before the nanofibers get deposited, suggesting that the solvent won’t pose toxicity problems, according to the paper. Cells sprayed with the PLGA nanofibers show no change in health after 24 hours. In lab tests, the nanofiber mats degraded completely over a 42-day period.

The polymer nanofiber mats are currently being improved and studied for upcoming surgical trials in laboratory animals.

Science fiction fans have been nursing their cuts and scrapes ever since the 1960 novel Dr. Futurity, in which Philip K. Dick wrote about art-derm - spray-on skin that could be directly applied to wounds.

Over her lacerated right shoulder he sprayed art-derm; it sealed off the open wound, halted bleeding, and prohibited infection.
(Read more about art-derm)

From In Situ Deposition of PLGA Nanofibers via Solution Blow Spinning via Chemical & Engineering News.

Scroll down for more stories in the same category. (Story submitted 3/27/2014)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Medical ")

Surgery In Space
' It was a ... coffin, form-fitted to Nessus himself...' - Larry Niven, 1972.

Organoids Galore!
'Runciter's body contained a dozen artiforgs...'- Philip K. Dick, 1969.

Please, Please Let There Be Regenerated Teeth
'Toothbud transplants...' - William Gibson, 1984.

First Biolimb Grown In Lab
A brand-new forelimb for some lucky rat.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Robots Take Our Jobs By Reading Our Instructions
'The Talk Between Robots radio...'

Surgery In Space
' It was a ... coffin, form-fitted to Nessus himself...'

Flimmer Navy Drone Flies And Swims
Launch the Flying Sub!

Taser Drones Now Legal In North Dakota
'I sent my eyes on their rounds and tended my gallery of one hundred-thirty changing pictures...'

Growing Metal In The Shape You Want
What more do you need, engineers?

Self-Healing Materials For Spacecraft
'It even had an inter-skin layer of gum that sealed the punctures...'

World's First Full-Colour, Flexible Thin-Film Reflective Display
'A wide sheet of clear material suddenly flared with light and swirling colour....'

Jazz AI Compliments Of DARPA
'I request that you feed the correlation between those dots and the levers of the panel into my memory banks.'

Tasty Space Lettuce!
Having tested, we tasted.

See LG OLED Wallpaper - Amazing Video
'... television that unrolled like a poster.'

Canada's Inflatable Space Elevator Tower
"...establish an elevator system linking Earth to space?"

Ekso Works Industrial Exoskeleton
'Earth's scientists [devised] rigid metallic clothing not unlike armor...'

Mother Robot Evolves Her Children
'The Robot Mother... the most dangerous thing in creation.'

Cheetah 2 Robot Now Leaps Obstacles To Get You
'The legs are long, curled way up to deliver power, like a cheetah's.'

Xiaoice Will Text You And Be Your Friend
'If you spoke English, results might be whimsical...'

Synthetic Coral To Clean The Seas?
'Numberless capillaries arranged in a belt around the smart coral reef...'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.