Spray-On Polymer Mats Heal Wounds Fast

Researchers have discovered that they can spray polymer nanofibers directly onto living tissues using an airbrush purchasable at any hardware store. These biodegradable mats of sticky fibers can seal surgical incisions and help them to heal.


(From PLGA nanofibers sprayed onto gloved hand)

Current methods for making the mats—such as electrospinning, which involves electric current—would damage living cells if the mats were made in situ. To devise a way to create the mats directly on the tissue, Kofinas and colleagues adapted a commercial airbrush, a tool more commonly used to apply paint.

They tinkered with different formulations of a biodegradable polymer, poly(lactic-co-glycolic acid), or PLGA, to find one that would work in the airbrush. By choosing a particular molecular weight of PLGA and concentration of acetone as the solvent, they could control the diameter of the resulting fibers. They ended up producing mats with fiber diameters of about 370 nm.

The researchers showed that the mats could seal diaphragm hernias and cuts to the lung, intestine, and liver in a pig. The acetone appears to evaporate before the nanofibers get deposited, suggesting that the solvent won’t pose toxicity problems, according to the paper. Cells sprayed with the PLGA nanofibers show no change in health after 24 hours. In lab tests, the nanofiber mats degraded completely over a 42-day period.

The polymer nanofiber mats are currently being improved and studied for upcoming surgical trials in laboratory animals.

Science fiction fans have been nursing their cuts and scrapes ever since the 1960 novel Dr. Futurity, in which Philip K. Dick wrote about art-derm - spray-on skin that could be directly applied to wounds.

Over her lacerated right shoulder he sprayed art-derm; it sealed off the open wound, halted bleeding, and prohibited infection.
(Read more about art-derm)

From In Situ Deposition of PLGA Nanofibers via Solution Blow Spinning via Chemical & Engineering News.

Scroll down for more stories in the same category. (Story submitted 3/27/2014)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Medical ")

Purdue Pharma Ready To Profit From OxyContin Use Or Addiction Recovery
'It may be organic damage. It may be permanent. Time'll tell, and only after you are off Substance D for a long while.' - Philip K. Dick, 1977.

Organaut! Russians 3D Print Living Tissue In Space
'For a while your colonists will have to come up [to orbit] to the Hospital...' - Larry Niven, 1968.

MIT Scientists Create 'Peek-a-Boo Prober' From Jetsons
Well, George, it's the latest thing.

Wound Healing With Wearable Nanogenerators
'... forcing the energy transfer which allowed him to ... erase the other internal-external damage.' - Frank Herbert, 1972.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Unfurl The Future! Huawei Mate X versus Galaxy Fold
'A paper thin polycarbon screen unfurled silently from the top of the unit and immediately grew rigid.'

Amazon Echo And Google Home Should Have Morality Software
'The Dwoskin Morality Rating-Computer could 'spot the slightest tendency to deviation' from the social norm...'

China Building Robot Wives
'Want a life-companion, a pleasant one?'

China Social Credit System Like State-Run Whuffie
'At least there was no mandatory Whuffie check on the monorail platform...'

Project Soli Radar Gesture Chip Now FCC Approved
'He waved his hand and the circuit switched abruptly.'

Stan, Robot Valet, Will Drag Your Car Away
'He activated the grapple tracks. '

Jibo Home Robot Says Goodbye, Is Killswitched
'It resembles an oyster....'

Johns Hopkins Says Asteroid Deflection Will Be Difficult
'This obelisk is one huge deflector mechanism...'

Fabric Automatically Cools Or Insulates Based On Environment
'...a high-efficiency filter and heat-exchange system.'

Deepfakes From OpenAI GPT-2 Algorithm
'How can you compete with an IBM heavy-duty logomatic analogue?'

John Deere Self-Driving Tractor
'The huge plow... seemed to shake itself - and began to move back southward.'

North Focals Smart Glasses Provide Augmented Reality In Style
'The world ... is drenched in unfamiliar information all the way to the horizon.'

Tesla Driver Caught Napping Behind The Wheel
'Mary Risling settled back for a little nap...'

Hayabusa 2 To Begin Asteroid Mining
'We must dig down, and then doubtless we shall find the metal.'

Ionocraft Drone Powered By Electrohydrodynamic Thrust
'He saw one hiss by him as he rounded the corner, trailing a short whip antenna...'

Purdue Pharma Ready To Profit From OxyContin Use Or Addiction Recovery
'It may be organic damage. It may be permanent. Time'll tell, and only after you are off Substance D for a long while.'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.