Small Human Livers Grown In Lab

Small human livers, about an inch in diameter and weighing about 20 ounces, have been grown in the lab at the Institute for Regenerative Medicine at Wake Forest University Baptist Medical Center.

To engineer the organs, the scientists used animal livers that were treated with a mild detergent to remove all cells (a process called decellularization), leaving only the collagen “skeleton” or support structure. They then replaced the original cells with two types of human cells: immature liver cells known as progenitors, and endothelial cells that line blood vessels.

The cells were introduced into the liver skeleton through a large vessel that feeds a system of smaller vessels in the liver. This network of vessels remains intact after the decellularization process. The liver was next placed in a bioreactor, special equipment that provides a constant flow of nutrients and oxygen throughout the organ.

After a week in the bioreactor system, the scientists documented the progressive formation of human liver tissue, as well as liver-associated function. They observed widespread cell growth inside the bioengineered organ.

Artificially grown livers and other organs for transplantation was one of the core issues discussed by science fiction writer Larry Niven in his 1968 novel A Gift from Earth:

I'm sure we can offer free access to the heartbeasts and liverbeasts and so forth. For a while your colonists will have to come up to the Hospital to get treatment with the ramrobot symbiots, but eventually we can build culture tanks in Gamma and Delta and Eta."
(Read more about Larry Niven's artificially grown organs)

Via Wake Forest University press release.

Scroll down for more stories in the same category. (Story submitted 11/7/2010)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Medical ")

Robothread Robotic Worms Crawling Through Your Brain
Perfect for clot-busting in the human brain. No Raquel Welch and no lasers, though.

Skin Electronics Can Show Electrocardiogram
'... the young men in the streets who applied polyimde OLED body film to their bared shoulders.' - Chen Qiufan, 2019.

Neurodevices For Consumers? Neuroethicists (And Philip K Dick) Say 'Caveat Emptor'
'They tried to use it today and it wouldn't work. No colors and no ceph patterns, neither one...' - Philip K. Dick, 1977.

BrainEx Restores Some Activity To Severed Pig Head
'... they placed the brain in a special solution, having all the properties of Nursing the brain cells.' - Edmond Hamilton, 1929.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Zephyr Solar-Electric Stratospheric Drone
'The planes flew continuously, twenty-four hours a day...'

Robot Hummingbird Hovers Biomimetically
'With a buzz... it started out on its journey.'

Harvest Water From Air With Sunlight
'The atmosphere yielded its moisture with reluctance.'

Capitalist Big Brother Co-Opts Regular Big Brother
'It was even conceivable that they watched everybody all the time.'

A Floating Cosmodrome
'...a single perfectly level platform, which rose so high above the water that it was not splashed by the waves.'

First Artificial Memory Formed In Animals
'Is an extra-factual memory that convincing?' Quail asked.

Maintain Your Megastructure
Megastructures have repair robots, which have repair robots, ad infinitum.

Venezuelans Teaching Your Self-Driving Car
‘She wouldn't stop until Antar had told her everything he knew...’

Robothread Robotic Worms Crawling Through Your Brain
Perfect for clot-busting in the human brain. No Raquel Welch and no lasers, though.

Vantablack BMW X6 Is Douglas Adams Approved
'It's so... black!' said Ford Prefect.

Humanoid Robot's Muscles Biomimic Ours
'It is remarkable that the long leverages of their machines are in most cases actuated by a sort of sham musculature...'

Animatronic Robotic Baby Exposed
'The birth of Machine, my robot child...'

Beijing HaiDiLao Robotic Hotpot Restaurant Now Flavored By Artificial Intelligence
'Kantos Kan led me to one of these gorgeous eating places where we were served entirely by mechanical apparatus.'

Plants of the Future - What Should They Be Like
'He almost choked in his astonishment. Mashed potatoes and brown gravy!'

China Deploys Robot Traffic Police
'The robot came up smooth and fast as a rocket...'

Better Than Dune Chromoplastic? This Guy Might Have Done It
'But when Old Father Sun departs, the chromoplastic reverts to transparency in the dark.'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.