 |
First Artificial Human Ovary
An artificial human ovary has been created by Brown University researchers. The intent is to provide the capability of maturing human eggs in the laboratory.
(Granulosa cell spheres marked with fluorescent green dye,
surrounded by artificial human ovary)
The artificial ovary marks the first time researchers have successfully created a three-dimensional environment that contains the three main types of ovarian cells: theca cells, granulosa cells, and the eggs, known as oocytes.The researchers broke ovarian cells out of human tissue using enzymes, and poured them into a mold made of agar, a gelatinous substance usually derived from algae. The different types of cells then assembled themselves into a honeycomb shape, with the theca and granulosa cells forming the structure. The egg cells, or oocytes, were inserted inside and bathed with hormones to stimulate the theca cells to produce androgen, and the granulosa cells to make estrogen.
"We took a different tack to rely on the inherent adhesiveness of cells to drive self-assembly," says Jeffrey Morgan, codirector of the Center for Biomedical Engineering at Brown, who led this aspect of the research. "In that nonadhesive environment, the cells will stick to each other and self-assemble a three-dimensional structure, and it conforms to the shape of our mold."
A functional artificial human ovary could help scientists understand the impact of environmental toxins or fertility drugs on human fertility. It could also be used to help women whose ovaries had been damaged.
Science fiction fans of course remember the somewhat more extensive artificial womb described by Aldous Huxley in his 1932 novel Brave New World:
...From the Social Predestination Room the escalators went rumbling down into the basement, and there, in the crimson darkness, stewing warm on their cushion of peritoneum and gorged with blood-surrogate and hormones, the foetuses grew and grew or, poisoned, languished into a stunted Epsilonhood.
Also, fans of Frank Herbert recall the procreative stump from his 1972 chiller Hellstrom's Hive.
Via Technology Review.
Scroll down for more stories in the same category. (Story submitted 9/24/2010)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion (Back On) ( 1 )
Related News Stories - (" Medical ")
CARMAT Bioprosthetic Total Human Heart Replacement
'George Walt's corporate existence proved the workability of wholly mechanical organs...'- Philip K. Dick, 1964.
Physical Exam? We've Got Apps
See the future of handheld, personal medical devices used with your smartphone.
Japan's Nursing Home Robot Plan
Let's make the Roujin Z-0001 Robotic Bed!
Mini-Livers Made By 3D Printer
Organlegging may not be the growth industry that some fear.
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Current News
MIT Robot Cheetah Video Shows Gait Transition
'The legs are long, curled way up to deliver power, like a cheetah's.'
TrackingPoint Smart Rifle
Not your typical 'smart bullet' approach.
'Hello, Computer!' Google Now Highlighted at IO13
'Hello, computer!'
Sky City's 220 Stories Are Go
'It rested among green parklands and... stood in total isolation, a glittering block of whites and flashing windows dotted with colors.'
CARMAT Bioprosthetic Total Human Heart Replacement
'George Walt's corporate existence proved the workability of wholly mechanical organs...'
Personal Sniffer Robots
'...The ticking combinations of the olfactory system of the hound.'
Physical Exam? We've Got Apps
See the future of handheld, personal medical devices.
The Interplanetary Internet, Vint Cerf Speaking
'This was the center of Interplanetary Communications.'
Drosophila Robotica, The Mechanical Fly
'... the Scarab [flying robot] buzzed into the great workroom as any intruding insect might...'
Robo-Raven Flapping Wing Robot Bird
'When he had first built them, they had been crude indeed, flying mechanisms with little more than a reflex-response unit.'
Japan's Nursing Home Robot Plan
Let's make the Roujin Z-0001 Robotic Bed!
Samsung Smart TVs With Gesture Control
'He waved his hand and the circuit switched abruptly.'
Swiss HCPVT Giant Photovoltaic 'Flower'
'...leaning against one of the slender stalks of a sunshade-photocell collector.'
Mini-Livers Made By 3D Printer
Organleggers may experience an employment downturn.
Smartphone Sensor System Tracks Gunfire
'Sound trackers on the roof could zero in on weapons action...'
Bacteria Now Make Biofuel Like Oil
'They have ... germs that eat pretty near anything, and produce oil as a waste product.'
