Smarter Rats Via Transgenic Over-Expression Of NR2B Gene

Hobbie-J is a transgenically-enhanced rat able to remember novel objects for three times longer than the average Long Evans female rat (the smartest rat strain).

Researchers from the Medical College of Georgia and East China Normal University developed Hobbie-J 's superior brainpower by transgenic over-expression of the NR2B gene, which in turn increased communication between NMDA receptor sites maybe a hundred milliseconds longer than normal, just enough to enhance learning and memory. NMDA receptors (and their NR2B subunits) are the controlling molecular structures for synaptic plasticity and memory.

Gene expression is translation of information encoded in a gene into protein or RNA. When done to a very high level, it is known as over-expression. The researchers wanted to determine whether the NR2B gene is “a universal genetic factor that acts as a rate-limiting molecule” across species. Here’s a short video showing the process of gene expression:


(Video on gene expression)

Science fiction fans have been pursuing the cheese of enhanced intelligence through the maze of research for decades. We all have our favorites; perhaps you're thinking of Flowers for Algernon, the 1958 short story by Daniel Keyes. In the story, Algernon is a laboratory mouse who has undergone surgery to increase his intelligence; the story is narrated by Charlie, the first person to undergo the procedure.

Via Hplus; thanks to Winchell Chung for the tip on this story.

Scroll down for more stories in the same category. (Story submitted 11/10/2009)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Biology ")

DNA May Contain Malware
'You were told to embed the logical pathogen.' - A. Reynolds and S. Baxter, 2016.

GMO Houseplant Cleans Your Air
Removes compounds too small to be captured by a HEPA filter.

Oil from Algae - Can It Be Done?
'We dump everything that's waste into the tanks, pump the oil off the top.' - Hal Clement, 1950.

Amazing 'Hybrid' Solar-Powered Sea Slug Does Photosynthesis
Thank goodness for Star Trek.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Purdue Pharma Ready To Profit From OxyContin Use Or Addiction Recovery
'It may be organic damage. It may be permanent. Time'll tell, and only after you are off Substance D for a long while.'

BloxVox Mutes Cellphone Convos
It's the polite thing to do, and has been the polite thing to do for about four generations.

Superfast Replicator: Volumetric Additive Manufacturing
I can't wait. Bring it on.

DNA May Contain Malware
'You were told to embed the logical pathogen.'

I Can't Resist Worm Robots
'Seen close it was not completely flexible...'

Rplate Digital License Plates Now Legal In Michigan
'Gragg's digital ink license plates ...'

Can Musk Starship Astronauts Use Magnetic Boots?
'Walking awkwardly in the magnetic boots that held him to the black mass of meteoric iron...'

Giant Dolphin Spotted On Jupiter!
'Now at last he could appreciate its real size and complexity...'

Musk's Starship An SF Fan's Dream Come True
Perfect for testing, perfect for fans!

TinyMobileRobots Are Sewer Sentinels
Every movie monster gets its start someplace.

Fishy Facial Recognition Now Possible
'Palenkis can identify random line patterns better than any other species in the universe.'

Spicy Tomatoes Created With Genetic Engineering
How about mashed potatoes and brown gravy?

Driverless Hotel Rooms Predicted In 1828
'Did you never see a moving house before?'

Yandex Self-Driving Taxi Is Very Smooth
'The big car was slowing down, its computer brain sensing an exit ahead.'

Shrimp Actually Made Of Algae Is A New Wave Food
Bring in that crop algae.

Cosplay Style Wings Could Work On Moon
'They're lovely! - titanalloy struts as light and strong as bird-bones...'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.