Smarter Rats Via Transgenic Over-Expression Of NR2B Gene

Hobbie-J is a transgenically-enhanced rat able to remember novel objects for three times longer than the average Long Evans female rat (the smartest rat strain).

Researchers from the Medical College of Georgia and East China Normal University developed Hobbie-J 's superior brainpower by transgenic over-expression of the NR2B gene, which in turn increased communication between NMDA receptor sites maybe a hundred milliseconds longer than normal, just enough to enhance learning and memory. NMDA receptors (and their NR2B subunits) are the controlling molecular structures for synaptic plasticity and memory.

Gene expression is translation of information encoded in a gene into protein or RNA. When done to a very high level, it is known as over-expression. The researchers wanted to determine whether the NR2B gene is “a universal genetic factor that acts as a rate-limiting molecule” across species. Here’s a short video showing the process of gene expression:


(Video on gene expression)

Science fiction fans have been pursuing the cheese of enhanced intelligence through the maze of research for decades. We all have our favorites; perhaps you're thinking of Flowers for Algernon, the 1958 short story by Daniel Keyes. In the story, Algernon is a laboratory mouse who has undergone surgery to increase his intelligence; the story is narrated by Charlie, the first person to undergo the procedure.

Via Hplus; thanks to Winchell Chung for the tip on this story.

Scroll down for more stories in the same category. (Story submitted 11/10/2009)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Biology ")

Hackers Insert Malware Into DNA
'They tied the memory to the bloodline and that was their record!' -

Worms Eat Plastic Now
'Slowly and inexorably, the rate of dissolution increased...' - Davis/Pedlar, 1971.

Mini-Brains In A Dish
'Cultured brains on a slab.' - Peter Watts, 1999.

NASA's Prototype Lunar Greenhouse For Mars And Moon
'In contrast to the airless desolation outside, the interior of this five-acre greenhouse was the one most desirable place to be.' - Raymond Z. Gallun, 1951.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

effie Automated Ironing Appliance
'Household Automata received an urgent task to develop production units of бытовые тканевые разглаживатели - a household fabric smoother.'

BabyX AI Real Enough For You
'...what's to keep me from showing face, Man? I'm showing a voice this instant... I can show a face the same way.'

We Could Downgrade Puerto Rico - And Thereby Save It
'It was cheaper to pay the refugees to go without up-to-the-minute equipment.'

Pegasus, Nvidia Supercomputer For Autonomous Driving
'...a 2045 convertible with a Hennis-Carleton positronic motor and an Armat chassis.'

Loihi Chip Mimics Human Brain's Neurons And Synapses
'You can hook a Thorsen tube into a control circuit... and the tube will "remember" what was done and can direct the operation...'

Self-Assembling Bacteria Build A Pressure Sensor
Nature is a master of fabricating structured materials consisting of living and non-living components.

3D Printed Artificial Muscles Are Stronger Than Yours
Bots don't need to work out.

Fog Computing (AKA Edge Computing) Ad Hoc Networks
'The tiny devices chirped their impulse codes at one another...'

Dubai Scorpion Police Hoverbike Ready To Pull Young Kirk Over
'Is there a problem, officer?'

Korean Tesla Model S Video 'Excelsior' Is Indeed Our Motto
'Improving man by bringing him close to Nature, while they combine the sensations of coasting with the interest of seeing the country well...'

HEXA Robotic Help For Plants
Then some unknown race had chanced upon the dreamers and decided to "help them out."

DIY Robot Shoots You In The Face
'...there were automatic guns that fired ligamine darts.'

A Bayesian Approach to Safe Imitation Learning For AIs and Robots
Um, how about that pension for the humans who serve as the models for robot behavior?

Qoobo Headless Robotic Therapy Cat Was Anne McCaffrey's Idea
'...used as surrogates in intense dependency cases.'

Autonomous Cars Talk To Each Other At MCity
'My cars talk to one another.'

PUFFER Robots - From Philip K DIck's Second Variety?
'Across the ground something small and metallic came, flashing in the dull sunlight of midday.'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.