Bioengineered Mouse Tooth Bud Successfully Implanted

A tiny bioengineered tooth bud has been successfully created and implanted in an adult mouse by Tokyo University researchers. They took epithelial cells and mesenchymal cells (about 50,000 each) from a mouse embryo and cultivated them together in a collagen-based medium to create a tiny tooth bud.

Here, we report a successful fully functioning tooth replacement in an adult mouse achieved through the transplantation of bioengineered tooth germ into the alveolar bone in the lost tooth region. We propose this technology as a model for future organ replacement therapies. The bioengineered tooth, which was erupted and occluded, had the correct tooth structure, hardness of mineralized tissues for mastication, and response to noxious stimulations such as mechanical stress and pain in cooperation with other oral and maxillofacial tissues.

(Bioengineered mouse tooth bud)

I first read about this idea in William Gibson's 1984 novel Neuromancer:

When Angelo smiled, revealing the razor-sharp canines of some large animal, Case was actually relieved. Toothbud transplants. He'd seen that before.
(Read more about toothbud transplants)

From Fully functional bioengineered tooth replacement as an organ replacement therapy via Pink Tentacle.

Scroll down for more stories in the same category. (Story submitted 8/7/2009)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 3 )

Related News Stories - (" Biology ")

Svalbard Seed Vault (aka Doomsday Vault) Gets Upgrades
'But they existed in the Life Bank, as did virtually every plant and animal that existed on Old Earth.' - John Varley, 1977.

China Melts Tibetan Permafrost To Plant Forest
'Can you give us a microwave spotlight?' - Niven, Pournelle, Flynn, 1995.

Hackers Insert Malware Into DNA
'They tied the memory to the bloodline and that was their record!' -

Worms Eat Plastic Now
'Slowly and inexorably, the rate of dissolution increased...' - Davis/Pedlar, 1971.



Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.






Current News

Save Your Brain's Connectome, Upload Yourself Elsewhere
'You've got remote storage. How regular is the update?'

TMS Decreases Belief In God, Increases Belief In Immigrants
'... setting up the same currents, the same basic ideas, in them all.'

Loomo Mini Transporter Robot Companion You Ride On
'Slowly the [robot] horse raised its head, wiggled its ears, blinked twice, gave a tentative whinny.'

Soft Robotics - Now With 3D Printed Sensors!
'A series of chemelectric afferent nerve-analogues, which permitted it to gauge to an ounce the amount of pressure necessary to snap a bone...'

AI Tool Lynx Insight And The Cybernetic Newsroom
'The structure,... was once a great homeostatic newspaper, the New York Times. It printed itself directly below us...'

Espresso Telescope Searches For Exoplanets
'These instruments were the wonderful ones our astronomers had perfected.'

Dune Fans! Metal-Organic Frameworks Make Science Fiction Real
'Dew collectors,' he muttered, enchanted by the simple beauty of such a scheme.

Manned Maneuvering Unit From 1984
'The glittering little rocket bolted to the black iron behind him.'

Astronaut Gets Younger In Space
'So what we're looking for now is not an antibiotic - an anti-life drug - but an anti-agathic, an anti-death drug...'

Blockchain Used To Verify Election Results
'Any adult could punch into the phone his or her code, followed by a yes or no.'

IJOP Integrated Joint Operations Platform China's Minority Report?
'All day long the idiots babbled, imprisoned in their special high-backed chairs...'

HushMe Bluetooth Device Reinvents The Hush-A-Phone
'Talking into a hush-a-phone which he had plugged into the telephone jack...'

Ultrathin Brain Needle Developed At MIT
Putting drugs into a selected cubic millimeter within the living brain.

Tesla Semi Truck Now At Work
Why wait? Tesla Semi now hard at work.

Illustris: The Next Generation Of Universe Simulation
'This digital device was ... A machine able literally to contain the Universe Itself...'

Scaly Yet Soft Robotic Snake
Love those robotic sneks.

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise | - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.