Software Tools Design Anti-Viral Cities

Is it possible to create a computer program that would allow the user to prevent the spread of a viral disease through proper design of cities and their infrastructure? Science fiction writer J.G. Ballard thought so.

In Super-Cannes: A Novel, published in 2000, he wrote about the idea. At one point the book's narrator is speaking with the corporate director of Eden-Olympia, a planned live/work community in southern France. The director refers to medical research that the narrator's own wife, a doctor, has been performing:

"She's running a new computer model," the director says, "tracing the spread of nasal viruses across Eden-Olympia. She has a hunch that if people moved their chairs a further eighteen inches apart they'd stop the infectious vectors in their tracks."

As it turns out, there has been work done on this idea. A demonstration project called Dynamical Network Design for Controlling Virus Spread shows the dynamics of the spread of the SARS virus in Hong Kong's eighteen districts if available resources are allocated in different ways:

Recently, problems of network management and design have become more and more important in such diverse areas as air traffic flow management and virus-spread control. Several problems of interest can be abstracted to the problems of allocating resources to a network based on its graph topology, so as to optimize its dynamic performance.

As an example, epidemic control can be viewed as reducing the average number of secondary infections produced during an infected individual's infectious period. The spatially inhomogeneous dynamics for epidemic spread in a population network are often represented using a class of models known as multi-group models. Using the multi-group model, the authors have posed and solved the problem of inhomogeneously allocating local resources to minimize spread (i.e., secondary infection population).


(From Dynamical Network Design for Controlling Virus Spread)

Another similar project is under way at Carnegie Mellon. Ph.D. student Sean Green is working on a set of tools to identify the best way to curb the spread of diarrheal illness in more than 192 countries worldwide. Infrastructure for sanitation is essential; but where do you get the biggest bang for your buck?

"We want to show where the money can be best spent in these communities where diarrheal illness kills more than two million people a year, and remains the third-leading cause of child mortality," said Green, a fourth year Ph.D. student in Carnegie Mellon's Engineering and Public Policy Department.

In research supported by the National Science Foundation, the Steinbrenner Institute for Environmental Education and Research and the Heinz Foundation, Green along with Carnegie Mellon professors Mitchell J. Small and Elizabeth A. Casman developed a pattern matching computer tool that uses a set of variables describing information about a country to try to pinpoint which policies are most effective at preventing disease outbreaks.

The Carnegie Mellon researchers report that the most important variable for reducing deadly diarrheal outbreaks among the factors that they considered is improved sanitation in rural areas.

Note: J.G. Ballard died just a couple of weeks ago; he will be missed.

From This Diseased Utopia and Dynamical Network Design for Controlling Virus Spread; see also Carnegie Mellon's Sean Green Uses Combination of Computer Tools And Artificial Intelligence to Predict Diarrheal Illness Globally.

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