'Volume Control' Ear Protein Uncovered
The nAChR protein found on sensory hair cells in the ear has been found to be a 'volume control' for the hearing system. It is part of a system that allows the ear to turn itself down to protect against permanent hearing loss.
To get a better handle on this sound-limiting system in the ear, the research team built on previous findings in the field and focused their efforts on the nAChR protein found on so-called sensory hair cells in the ear. Nerve cells from the brain release signals that are picked up by nAChR and turn down these sensory hair cells.
The team genetically altered a single building block in the nAChR protein and tested mice for their ability to hear. "This point mutation was designed to produce a so-called gain of function in which the inhibitory effect of ACh should be greater than normal," says Fuchs.
The altered mice were less able to hear soft sounds than normal mice, showing that the genetic alteration made in the nAChR protein did indeed further "turn down" the ear. The team then asked if the alteration in nAChR, and therefore the improved sound-blocking ability of these altered mice, also could protect from sound damage.
After blasting mice with 100-decibel sound, mice with the altered nAChR suffered less permanent hearing damage compared to normal mice. One of the study's authors, Paul Fuchs, Ph.D., professor of otolaryngology-head and neck surgery and co-director of the Center for Sensory Biology at the Institute for Basic Biomedical Sciences at Johns Hopkins, commented that there was "a real chance of finding ear-specific drugs in the future."
Writer Larry Niven remarks on this ability in his 1966 novel World of Ptavvs (I don't know if it was present in the novella published in 1965):
As he left the elevator Luke met the usual continuous roar. He waited ten seconds while his ears "learned" to ignore it; an essential mechanism, learned by most children before they were three.
Here's another quote from A Gift From Earth (1968):
The noise hit them as they opened the door. Matt stood still while his ears adjusted to the noise level - a survival trait his ancestors had developed when Earth's population numbered nineteen billion, even as it did that night, eleven point nine light-years away.
Via Eurekalert; thanks to an anonymous reader for pointing out the article and the sf connection (I hope I found the one you mentioned). Also, see another hundred or so ideas and inventions from the mind of Larry Niven.
Scroll down for more stories in the same category. (Story submitted 1/22/2009)
Follow this kind of news @Technovelgy.
| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
you like to contribute a story tip?
Get the URL of the story, and the related sf author, and add
Comment/Join discussion ( 2 )
Related News Stories -
Researchers Say 'Biohybrid Robot' - Clarke Said 'Biot'
'... The biological robots were not living creatures.' - Arthur C. Clarke, 1972.
Unique DNA To Foil Parts Counterfeiters
'... the only molecule, a unique protein amino acid, which could not be duplicated.' - Philip K. Dick, 1965.
Steerable Locusts Detect Explosives
Science fiction writers again provide a blueprint for the future.
Real Leather Without Cows Modern Meadow Biofabrication
'Plastissue, as any fool can see...' - WF Wallace, 1952,
Technovelgy (that's tech-novel-gee!)
is devoted to the creative science inventions and ideas of sf authors. Look for
the Invention Category that interests
you, the Glossary, the Invention
Timeline, or see what's New.
Cattle Avoidance Feature In Indian Autonomous Cars
'The driver went about the business of gently slipping the teflon-coated metal scoop beneath the first animal...'
Project KOVR Fashion Protection From Infosphere
'... the entire shroudlike membrane took on whatever physical characteristics were projected at any nanosecond.'
Twist Bioscience High Density Digital Data On DNA
'They tied the memory to the bloodline and that was their record!'
'We're Not Creating A Terminator' Say Russians About Gun-Wielding Robot Fedor
Nobody is thinking about the Terminator. Westworld, maybe.
Vantablack Now IMMEASURABLY Black
'a black coating now thatís ninety-nine percent absorptive...'
Mercedes-Benz Autonomous Taxi Fleet In 3 Years
'... the taxi utilized sophisticated electronic sensors to perceive its surroundings.'
Is 'The Pulsar Positioning System' Evidence For SETI?
'For a hyperspace jump, you need at least four beacons for an accurate fix.'
Someday, You Might Like VR Enough To Move In
'That barrier was going to melt away someday soon. The transhumanists had promised...'
Humans Use Mental Power For Turtle Slavery
Now we need to start looking for animals with fingers...
Solar-Powered Moisture Vaporator
'The atmosphere yielded its moisture with reluctance.'
DxtER! Tricorder Prize Won By Final Frontier Medical Devices
We've been waiting a long time for this, Star Trek fans.
President Trump's Wall As Otra Nation Hyperloop
'...an hollow tube must be constructed the whole distance... as to admit a four wheeled carriage...'
Pickup Lines From Artificial Intelligences
'They hate us, you know... The humans. They'll stop at nothing.'
Pooper Scooper Drone Robot Watchdog 1
'Robots pick up the garbage and junk...'
Cassie Robot Brings AT-ST Walker To Life
There's even a log test!
Hundreds Of Robot Lawnmowers Invade Texas Town
'The mower reached the edge of the lawn, clucked to itself...'
More SF in the News Stories
More Beyond Technovelgy science news stories