Diabetes Tattoo Tests For Glucose Levels

A diabetes tattoo might be just the thing to relieve diabetes sufferers of the constant pain of needle sticks. Most monitoring methods require that a blood sample be taken using a needle; researchers have long sought a non-invasive test method.


(Fluorescent polymer microbeads for diabetes tattoo)

Gerard Cote, biomedical engineering professor in the Dwight Look College of Engineering, is testing an experimental system using fluorescent polymer microbeads implanted just under a patient's skin. Glucose levels affect how much light the beads emit, which could be measured with a wristwatch-like monitor.

The experimental microgel beads, injected just under the skin, are too big to enter cells - unlike tattooing, in which cells absorb the pigment. Instead, the beads remain in the spaces between the cells, called the interstitial spaces. Fluid in those spaces contains water and glucose molecules small enough to pass through the PEG and reach the fluorophore-tagged polymers. Cote said the level of glucose in interstitial fluid is related to the blood glucose level that's measured by the traditional needle-stick method.

The dextran molecules bind to the conA molecules. Together, under light from a laser or light-emitting diode, they emit a certain color under fluorescence. However, when glucose enters the picture, it competes with dextran, displacing the dextran molecules and binding to the conA. The fluorescent color changes according to the amount of glucose present.

In preliminary studies, the researchers injected the microbeads under a rat's skin and found that the rat tolerated the implant. The beads did fluoresce under the rat's skin and indicated a change in glucose level.

Active tattoos can be found in various sf works; consider the subdermal microchannels from the 1985 cyberpunk classic Stone Lives by Paul Di Filippo:

June's body is a tracery of lambent lines, like some arcane capillary circuitry in the core of Mao/K'ung Fu-Tzu. Following the current craze, she has had a subdermal pattern of micro-channels implanted. The channels are filled with synthetic luciferase, the biochemical responsible for the glow of fireflies.
(Read more about Di Filippo's Subdermal Microchannels)

A similar idea is used in Nova Swing by M. John Harrison.

Don't miss these unusual tattoo stories:

Via Texas A&M Engineering: Fighting diabetes where It hurts. Thanks to reader KafirCake for the tip on the story.

Scroll down for more stories in the same category. (Story submitted 12/1/2007)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 1 )

Related News Stories - (" Medical ")

Organaut! Russians 3D Print Living Tissue In Space
'For a while your colonists will have to come up [to orbit] to the Hospital...' - Larry Niven, 1968.

MIT Scientists Create 'Peek-a-Boo Prober' From Jetsons
Well, George, it's the latest thing.

Wound Healing With Wearable Nanogenerators
'... forcing the energy transfer which allowed him to ... erase the other internal-external damage.' - Frank Herbert, 1972.

EXPLORER, The First Total-Body Scanner
'The object is built up of an infinite series of plane layers, at the focus of the ray...' - Jack Williamson, 1930.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

 

Current News

Fishy Facial Recognition Now Possible
'Palenkis can identify random line patterns better than any other species in the universe.'

Spicy Tomatoes Created With Genetic Engineering
How about mashed potatoes and brown gravy?

Driverless Hotel Rooms Predicted In 1828
'Did you never see a moving house before?'

Yandex Self-Driving Taxi Is Very Smooth
'The big car was slowing down, its computer brain sensing an exit ahead.'

Shrimp Actually Made Of Algae Is A New Wave Food
Bring in that crop algae.

Cosplay Style Wings Could Work On Moon
'They're lovely! - titanalloy struts as light and strong as bird-bones...'

Tesla Model 3 Has Outside Speaker Grille
Robert Heinlein does it again.

Arizona Luddites Attack Self-Driving Vehicles
'Trucks don't drive by themselves...' Or do they?

Organaut! Russians 3D Print Living Tissue In Space
'For a while your colonists will have to come up [to orbit] to the Hospital...'

WINE Spacecraft To Extract Water From Asteroids
'Yes, strangely enough there was still sufficient water beneath the surface of Vesta.'

Japanese Swordsmiths Take On Asteroids
'... a tiny, rocket-powered projectile, drove towards the mysterious bulk.'

Saturn's Rings To Vanish, Let's Mine Them While We Can
'...the valuable shards of what had once been satellites.'

Humans Could Take Up A LOT Less Space
We'd have a lot more room for gardening...

Implosion Fabrication Shrinks 3D Objects To Nanoscale
'Carter had watched miniaturization a hundred times...'

GMO Houseplant Cleans Your Air
Removes compounds too small to be captured by a HEPA filter.

Nova Meat Can 3D Print Your Dinner
Printing out chicken nuggets.

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.