Science Fiction Dictionary
A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

 

Limb Regeneration Grows Closer

How does limb regeneration work in animals like salamanders? If you cut off their tails, they are able to completely recreate the missing limb, including bones, muscle, skin, blood vessels and nerves.

In salamanders, new tissues come from a tumorlike mass of cells that forms at the site of the injury, called the blastema. Until now, most scientists thought that the blastema contained a population of stem cells that had become pluripotent--capable of giving rise to all the needed tissues.

However, new research published in Nature seems to indicate that the mechanism is simpler than previously supposed. An experiment designed by Elly Tanaka at the Center for Regenerative Therapies, in Dresden, Germany employed a new method for tracking what happens in the axolotl when it is injured.


( Schwann cells are shown here in a salamander limb )

The researchers first created transgenic axolotls that carried green fluorescent protein (GFP) in their entire bodies. When the animals were still embryos, the researchers removed a piece of tissue from the limb region of the transgenic animals and transplanted the tissue into the same location in nontransgenic axolotls. The transplants were incorporated into the growing body as normal cells, and when the limb of the transplant recipients were then severed, the researchers could track the fate of the fluorescent cells as the limb regrew.

The researchers used this method to track the fate of cells of the inner and outer skin, muscles, and cartilage, as well as Schwann cells, which insulate nerve fibers. They found that, contrary to previous evidence, muscle cells at the amputation site only become muscle cells in the new limb. Other cell types also stuck to their previous identities; the only exception, Tanaka says, is that cells of the inner layers of skin and cartilage seem to be able to transform into one another.

Frank Herbert wrote about the idea of limb regeneration in his appropriately named "axolotl tank" from his 1969 novel Dune Messiah:

"Even in defeat," Edric said, "your father's Sardaukar did not abandon wisdom. Let us suppose a wise Sardaukar commander recognized the swordmaster in a corpse his men had slain. What then? There exist uses for such flesh and training . . . if one acts swiftly..."

"A Tleilaxu ghola," Irulan whispered...

...Edric said. "...let us assume that our wise Sardaukar commander had Idaho's corpse preserved for the axolotl tanks.
(Read more about Herbert's axolotl tank)

From MIT's Technology Review.

Scroll down for more stories in the same category. (Story submitted 7/3/2009)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 5 )

Related News Stories - (" Medical ")

The Autonomous Robotic Urethral Catheter - Would You Use It?
'It'll snake its way in on its own.'

OrganEx Revives The Organs In Dead Pig
'Wakened into half-life activity one hour a month...' - Philip K. Dick, 1969.

Prototype 3D Printer Could Print Arteries In Seconds
'... in the tank the new body and the new mind and memory and life has taken almost instant form.' - Clifford Simak, 1963.

NextSense Earbuds Spy On Your Brain
'Your cephalochromoscope that cost you nine hundred dollars... colors and ceph patterns...' - Philip K. Dick, 1977.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

Science Fiction Timeline
1600-1899
1900-1939
1940's   1950's
1960's   1970's
1980's   1990's
2000's   2010's

Current News

New Train Station Offers Minority Report-Style Signs
A whole new world awaits you, John Anderton!

The Autonomous Robotic Urethral Catheter - Would You Use It?
'It'll snake its way in on its own.'

The Far Side Of The Moon, By NASA (2015) And By PAUL (1932)
"We had leisure to make a thorough observation of the hidden side of earth's satellite."

LoadRunner Robot Works Alone, Or In A Group
'They marched in unison, seven of them...'

Sierra Space Inflatable LIFE Habitat Burst Pressure Test
'It was like being inside a balloon...'

Longest Immersed Tunnel Will Connect Denmark and Germany
'... iron tubes... the ends of the tubes were joined to each other...to preserve it from the action of the seawater.'

Alcohol-Sensing Cars - NTSB Catches Up With Philip K. Dick (1963)
'Mr. Garden, you are in no condition to drive....'

Solar-Powered Remote-Control Cockroaches!
'A cable, here, from the controller to the interface plug... wires from that to the brain.'

SolarBotanic Tree For Solar Energy - Would You Need A Forest, Or Just One?
'The slender stalks of a sunshade-photocell collector...'

Metaverse Hardware - Run And Flail Like A Maniac, Or Lie Quietly?
'Holodeck 4 was waiting to be programmed...'

Robot Food Delivery Coming To Campus Near You
'... he rewired the delivery robot so that it would serve him midnight snacks.'

Are Craiyon Images Puddinged, ala Philip K. Dick?
'I stood in line for half an hour for this, and it's just a blob!'

Hip'Safe Airbag For Seniors, From Helite
'Other airbags go off around her torso and pelvis...'

Soulaje Self-Administered Euthanasia Wearable Prototype
'A young man... advanced with nervous strides along the gravel path which leads to the bronze doors of the Lethal Chamber.'

Midjourney AI Creates 'Théâtre D'opéra Spatial', Wins Art Fair First Prize
'... we'll give him in his brain what he needs for creation.'

Mobot Robot Tests Smartphone Apps With Its Finger
'Rapidly, purposefully, the metallic fingers moved over the key-boards...'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.