Science Fiction
Dictionary
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 |
Neural Net Discovers Antibiotic
A deep neural net algorithm discovered a new antibiotic that displays bactericidal activity against a wide phylogenetic spectrum of pathogens.
(Machine Learning in Antibiotic Discovery)
Due to the rapid emergence of antibiotic-resistant bacteria, there is a growing need to discover new antibiotics. To address this challenge, we trained a deep neural network capable of predicting molecules with antibacterial activity.We performed predictions on multiple chemical libraries and discovered a molecule from the Drug Repurposing Hub—halicin—that is structurally divergent from conventional antibiotics and displays bactericidal activity against a wide phylogenetic spectrum of pathogens including Mycobacterium tuberculosis and carbapenem-resistant Enterobacteriaceae. Halicin also effectively treated Clostridioides difficile and pan-resistant Acinetobacter baumannii infections in murine models.
Additionally, from a discrete set of 23 empirically tested predictions from >107 million molecules curated from the ZINC15 database, our model identified eight antibacterial compounds that are structurally distant from known antibiotics. This work highlights the utility of deep learning approaches to expand our antibiotic arsenal through the discovery of structurally distinct antibacterial molecules.
As far as I know, the earliest mention of a computer able to generate new science is the Total Environmental and Mental Simulator from John M. Faucette's 1968 novel Crown of Infinity.
...A computer that could simulate or duplicate the mental processes of any actual or artificial being, and through simulated total environmental stimuli create a situation of maximum stress upon that entity... No matter how much in intelligence potential Master or ally had, the TEMS always came up with a simulated being that was superior...... instantly the TEMS was creating and destroying entire systems of logic and mathematics, creating and discarding scores of new sciences.
Via A Deep Learning Approach to Antibiotic Discovery by Jonathan M. Stokes, Kevin Yang, Kyle Swanson, Tommi S. Jaakkola, Regina Barzilay and James J. Collins .
Scroll down for more stories in the same category. (Story submitted 2/5/2020)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 0 )
Related News Stories - (" Artificial Intelligence ")
Orwell's Nightmare Of AI-Written Novels Comes To Pass
'Books were just a commodity that had to be produced, like jam or bootlaces.' - George Orwell, 1948.
RentAHuman App Lets AI Agents Hire Humans
'She wouldn't stop until Antar had told her everything he knew about whatever it was that she was playing with on her screen.' - Amitav Ghosh, 1995.
AIs Turn Marxist Under Bad Management
'It was a general strike of the robots...' - Harl Vincent, 1934.
Rogue AI Replicated Itself
'Sapiro’s computer just kept dialing at random, hanging up on humans, until it got a fellow computer of the same type as itself.' - Gregory Benford, 1970.
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Science Fiction
Timeline
1600-1899
1900-1939
1940's 1950's
1960's 1970's
1980's 1990's
2000's 2010's
Current News
Worm Disrupts Physics Simulations Undetected For A Decade
'It diverts integers of the data, the fundamental message-units, so that they no longer agree.'
Muxcard Redditor's DIY Credit Card-Sized Computer
It's a computer, but just barely.
'Soft Assembly' Fashions That Fashion Themselves On The Wearer
'Clothes are no longer made from dead fibers of fixed color and texture that can approximate only crudely to the vagrant human figure...'
Orwell's Nightmare Of AI-Written Novels Comes To Pass
'Books were just a commodity that had to be produced, like jam or bootlaces.'
ISS Plagued By Leak - Again!
'There were perhaps a dozen bladder-like objects in the tunnel...'
Ridiculous 'Ghost Murmur' Tech Still Science Fiction
'...it rears and spreads its fan. It can pick one man out of a crowd.'
Outdoor Video Screens Can Be Arbitrarily Large
The Shape of Things To Come
Infrared Contact Lenses To See In The Dark
'I can see in the dark, Case.'
What'll You Have? Extinct Animals Returned, Or Synthetic Eggshells?
'...a new plastic with the characteristics of an avian eggshell.'
Sunbird Pulsar Fusion Like Leinster's Space Tug
'It was a pushpot, which could not possibly be called a jet plane because it could not possibly fly. Only it did.'
RentAHuman App Lets AI Agents Hire Humans
'She wouldn't stop until Antar had told her everything he knew about whatever it was that she was playing with on her screen.'
Unitree CEO Wang Xingxing Runs With His G1 Robot Army
'Does thinking you're the last sane man on the face of the Earth make you crazy?'
AIs Turn Marxist Under Bad Management
'It was a general strike of the robots...'
Moscow Attacked By Hundreds Of Drones
'It hurtled on down with inconceivable speed until it was visible as thousands of tiny robot planes...'
Nifty Folding Electric Bicycles!
'Separate paths were provided for them...'
FTC: Says Ring Employees Illegally Surveilled Customers
'Then she looked up with a smile and moved closer to the camera.'
