Science Fiction
Dictionary
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 |
Neural Net Discovers Antibiotic
A deep neural net algorithm discovered a new antibiotic that displays bactericidal activity against a wide phylogenetic spectrum of pathogens.
(Machine Learning in Antibiotic Discovery)
Due to the rapid emergence of antibiotic-resistant bacteria, there is a growing need to discover new antibiotics. To address this challenge, we trained a deep neural network capable of predicting molecules with antibacterial activity.We performed predictions on multiple chemical libraries and discovered a molecule from the Drug Repurposing Hub—halicin—that is structurally divergent from conventional antibiotics and displays bactericidal activity against a wide phylogenetic spectrum of pathogens including Mycobacterium tuberculosis and carbapenem-resistant Enterobacteriaceae. Halicin also effectively treated Clostridioides difficile and pan-resistant Acinetobacter baumannii infections in murine models.
Additionally, from a discrete set of 23 empirically tested predictions from >107 million molecules curated from the ZINC15 database, our model identified eight antibacterial compounds that are structurally distant from known antibiotics. This work highlights the utility of deep learning approaches to expand our antibiotic arsenal through the discovery of structurally distinct antibacterial molecules.
As far as I know, the earliest mention of a computer able to generate new science is the Total Environmental and Mental Simulator from John M. Faucette's 1968 novel Crown of Infinity.
...A computer that could simulate or duplicate the mental processes of any actual or artificial being, and through simulated total environmental stimuli create a situation of maximum stress upon that entity... No matter how much in intelligence potential Master or ally had, the TEMS always came up with a simulated being that was superior...... instantly the TEMS was creating and destroying entire systems of logic and mathematics, creating and discarding scores of new sciences.
Via A Deep Learning Approach to Antibiotic Discovery by Jonathan M. Stokes, Kevin Yang, Kyle Swanson, Tommi S. Jaakkola, Regina Barzilay and James J. Collins .
Scroll down for more stories in the same category. (Story submitted 2/5/2020)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 0 )
Related News Stories - (" Artificial Intelligence ")
'AI Assistants' Are Actually Less Reliable For News
'Most men updated their PIP on New Year's Day...' - Arthur C. Clarke, 1978.
Will AIs Give Better Results If You're Rude To Them?
'I said, "Listen up, motherf*cker.' - John Varley, 1983
Chinese Tokamak Uses AI To Keep Fusion Plasma Stable
'Guy named Otto Octavius winds up with eight limbs... What are the odds?'
Alexa+ And Its AI Brain Improvements
'What's it do?' he asked. 'It amuses.' Philip K. Dick, 1965.
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Science Fiction
Timeline
1600-1899
1900-1939
1940's 1950's
1960's 1970's
1980's 1990's
2000's 2010's
Current News
Musk Idea Of Cars Talking To Each Other Predicted 70 Years Ago
'My cars talk to one another.'
Elegant Bivouac Shelter Produces Water And Electricity
'There was nowhere on the planet where science and technology could not provide one with a comfortable home...'
X-Control Janus-1 A Suitcase Aircraft
'You will notice that it... fits the suitcase nicely.'
'AI Assistants' Are Actually Less Reliable For News
'Most men updated their PIP on New Year's Day...'
YES!! Remote Teleoperated Robots predicted by Technovelgy!
'...a misshapen, many-tentacled thing about twice the size of a man.'
Will Robots Ever Fold Landry?
Where have you gone, Mrs. Robinson?
Will AIs Give Better Results If You're Rude To Them?
'I said, "Listen up, motherf*cker.'
Cybertruck Robotic Arm F10 Drone Launch!
Drone away!
Black Fungus Blocks Radiation
'You were surrounded by Astrophage most of the time'
Liuzhi Process Now In Use In China
'He was in a high-ceilinged windowless cell with walls of glittering white porcelain.'
Reflect Orbital Offers 'Sunlight on Demand' And Light Pollution
'I don't have to tell you about the seven two-mile-diameter orbital mirrors...'
Will Robots Become Family Caregivers?
'The robant and the tiny old woman entered the control room slowly...'
Chinese Tokamak Uses AI To Keep Fusion Plasma Stable
'Guy named Otto Octavius winds up with eight limbs... What are the odds?'
Time Crystals Can Now Be Seen Directly
'It is as you thought when you constructed the time crystal, my master Vaylan.'
RoboBallet The Dance Of Cooperative Robots
'...an integrated seven-unit robot team.'
Chrysalis Generation Ship to Alpha Centauri
'This was their world, their planet —
this swift-traveling, yet seemingly moveless vessel.'
