Science Fiction Dictionary
A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

 

Epigenetic Memory's On/Off Switch Found

Epigenetics is the study of inheritable changes in gene expression not directly coded in our DNA. It appears that our life experiences can be passed on to our children, and to future generations, by this mechanism.


(From Transgenerational Small RNA Inheritance)
The duration of epigenetic responses underpinning
transgenerational inheritance is determined by an active
mechanism relying on the production of small RNAs
and modulation of RNAi factors, dictating whether ancestral
RNAi responses would be memorized or forgotten.
(credit: Leah Houri-Ze’evi et al./Cell)

“Until now, it has been assumed that a passive dilution or decay governs the inheritance of epigenetic responses,” said Oded Rechavi, PhD, from TAU’s Faculty of Life Sciences and Sagol School of Neuroscience. “But we showed that there is an active process that regulates epigenetic inheritance down through generations.”

The scientists discovered that specific genes, which they named “MOTEK” (Modified Transgenerational Epigenetic Kinetics), were involved in turning epigenetic transmissions on and off.

“We discovered how to manipulate the transgenerational duration of epigenetic inheritance in worms by switching ‘on’ and ‘off’ the small RNAs that worms use to regulate [these] genes,” said Rechavi.*

These switches are controlled by a feedback interaction between gene-regulating small RNAs, which are inheritable, and the MOTEK genes that are required to produce and transmit these small RNAs across generations.

The feedback determines whether epigenetic memory will continue to the progeny or not, and how long each epigenetic response will last.

The first time I read about this idea was in an excellent series of fantasy novels by Barbara Hambly. In her 1982 Darwath trilogy, she writes about how wizards of several thousand years ago succeeded in tying information to the DNA of selected individuals. In the story, several people from 1980's California find themselves transported across the Void to another planet and the Realm of Darwath. They face a deadly species of queerly magical beings - the Dark - who destroyed civilization thousands of years ago. Everything that was made of paper (like books and records) were burned to stave off attacks by the Dark. Tying memories to a few suitable bloodlines was the only way to preserve a record of that period that would endure.

"We have all talked of the heritable memories of the House of Dare," she went on... maybe the old wizards, the engineers who raised the Keep, knew that records do get lost, especially when, as you said, fire is the principal weapon."

Gil's finger stabbed out like a sword. "They tied the memory to the bloodline and that was their record! A record that wouldn't get lost and couldn't be destroyed."

Via KurzweilAI.

Scroll down for more stories in the same category. (Story submitted 3/29/2016)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Biology ")

Lunar Biorepository Proposed For Cryo-Preservation Of Earth Species
'...there was no one alive who had ever seen them. But they existed in the Life Bank.' - John Varley, 1977.

Let's Make Slaver Sunflowers! Engineering Plants To Reflect Light
'The mirror-blossom was a terrible weapon.' - Larry Niven, 1965.

Machete-Wielding Philodendron Isn't Going To Take It Anymore
'The tree ended its wild larruping, stood like a dreaming giant liable to wake into frenzy at any moment.' - Eric Frank Russell, 1943.

Tsunami Forecasts Improved By Ionosphere Signals
'Swifter than any tide could ebb, the water was receding from the shore.'

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

Science Fiction Timeline
1600-1899
1900-1939
1940's   1950's
1960's   1970's
1980's   1990's
2000's   2010's

Current News

Drones Recharge In Mid-Air Like Jets Refuel!
'...nurse drones that would cruise around dumping large amounts of power into randomly selected pods.'

Australian Authors Reject AI Training Of Llama
'It's done with a flip of the third joint of the tentacle on the down beat.'

Is China Mining Helium-3 On The Moon's Farside?
'...for months Grantline bores had dug into the cliff.'

Maybe It's Too Soon To Require Autonomous Mode
'I hope all those other cars are on automatic,' he said anxiously.

Is Agentic AI The Wrong Kind Of Smartness?
'It’s smart enough to go wrong in very complicated ways, but not smart enough to help us find out what’s wrong.'

Heat Waver - The First Ever Combo Solar Collector And Wind Turbine
'...like a spray of tulips mounted fanwise.'

Tesla 'Fleet Response Agents' Bolster FSD Autonomy
'You hate the whole idea that some bored drone pusher in a remote driving centre has got your life... in his hands.'

Mori3 Autonomous Shapeshifting Robot
'My homeland is being threatened by the Replicators. Thus far all attempts to stop them have failed.'

Tesla Seeks 'Tesla Robotaxi' And 'Robobus' Trademarks Ignoring Prior Art
'A robobus had just rolled up to the curb.'

Scary Grid Safety Robots
'The ultimate horror for our paranoid culture...'

Does AI Provide A Way Forward For Talk Therapy
'And there in the next room by the sofa sat a familiar suitcase, that of his psychiatrist Dr. Smile.'

Robotic Barber Programmed With a Number of Styles
'He found a barber shop which, he thought, would be good for an idle hour.'

Humanoid Boxing Robot KO's Opponent - It's A Knockout!
'Thirty rounds of fighting is tough work. Even for machines.'

Caterpillar Electric Mining Loader Not Yet Ready For Moon
'...the excavations were already in progress, for he saw gray slopes of rubble.'

Centipede Robots Down On The Farm
'...the walking mills of Puffy Products began to tread delicately on their centipede legs across the wheat fields of Kansas.'

Anthropic's Claude AI Creates Legal Citation From Whole Cloth
'Here is a Clerk that would work incessantly, and neither eat, sleep, want payment, or grumble.'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.