Science Fiction Dictionary
A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

 

Beating Mini-Heart Grown In Lab

Scientists at Abertay University in the UK have grown miniature beating human hearts in which they can induce heart disease, enabling them to test newly developed drugs.


(Hypertrophic heart cell; green shows targets for drugs)

Prof. Zhelev and his team have managed to induce ventricular hypertrophy in the mini hearts - a form of heart disease characterized by thickening of the heart muscles, which makes it more difficult for blood to be pumped around the body.

The team used stem cells to grow the hearts, which are only 1 mm in diameter and contract at approximately 30 beats per minute.

Once grown, the scientists infuse the hearts with chemicals that cause abnormal growth of heart cells, known as cardiomyocytes. This causes the heart to become hypertrophic.

Biosensors are then used to pinpoint the molecules and their pathways involved in ventricular hypotrophy, allowing the team to develop drugs that target such molecules in the hope they will halt heart damage.

And Prof. Zhelev says one of the drugs they have tested - a compound that has recently completed phase 2 clinical trials in cancer patients - has already shown promise. The drug was able to stop hypertrophy in its tracks. Prof. Zhelev says:

I don't know of any specific references to the idea of artificial organs being used for research. However, in his 1969 masterpiece Ubik, Philip K. Dick introduced the idea of implanting secondary artificial organic organs - perhaps smaller versions of the originals as backup.

Probably Runciter's body contained a dozen artiforgs, artificial organs grafted into place in his physiological apparatus as the genuine, original ones, failed.
(Read more about Dick's artiforgs)

Via Medical News.

Scroll down for more stories in the same category. (Story submitted 6/28/2014)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Medical ")

Illustrating Classic Heinlein With AI
'Stasis, cold sleep, hibernation, hypothermia, reduced metabolism, call it what you will - the logistics-medicine research teams had found a way to stack people like cordwood and use them when needed.' - Robert Heinlein, 1956

Brainoware Reservoir Computation Of Biological Neural Networks
'Head cheese. Cultured brains on a slab.' - Peter Watts, 1999.

Forward CarePod The AI Doctor's Office
'It's an old model,' Rawlins said. 'I'm not sure what to do.'

Octopus Suckers Inspire Transdermal Patches
'...a capsule which he placed against his wrist.' - Philip K. Dick, 1960.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

Science Fiction Timeline
1600-1899
1900-1939
1940's   1950's
1960's   1970's
1980's   1990's
2000's   2010's

Current News

Europa Clipper Plate Carries A Special Message
'...a universal cryptogram — yet it is one which can be interpreted by any intelligent creature on any planet in the Solar System!'

Micro-Robots Are Smallest, Fully Functional
'With a whir, the Scarab shot from the concealing shadows of the corner where it had hidden itself.'

AI Enhances Images Your Brain Sees
'I could have sworn the psychomat showed pictures almost as sharp and detailed as reality itself'

Illustrating Classic Heinlein With AI
'Stasis, cold sleep, hibernation, hypothermia, reduced metabolism, call it what you will - the logistics-medicine research teams had found a way to stack people like cordwood and use them when needed.'

Deflector Plasma Screen For Drones ala Star Wars
'If the enemy persists in attacking or even intensifies their power, the density of the plasma in space will suddenly increase, causing it to reflect most of the incoming energy like a mirror.'

DIY Robotic Hand Made After Loss Of Fingers
'I made them... with the fine work of the watchmaker...'

Cheap Drunk Driver Detection From UofM
"Look, I can drive... Start, darn it!"

Can A Human Land A SpaceX Rocket On Its Tail?
'If she starts to roll sideways — blooey! The underjets only hold you up when they’re pointing down, you know.'

Robot Snakes No Longer Stopped By Stairs
'...she dropped her hands from the wheel, took the robot snake from his box.'

Has Turkey Been Stealing Rain From Iran?
Can one country take another's rain?

We Need To Build Anti-Drone Systems For Civilian Spaces
'the real border was defended by ...a swarm of quasi-independent aerostats...'

SensorWake Scent-Based Alarm Clock
'The odalarm awoke Jorj X. McKie with a whiff of lemon.'

AI Worms That Spread
'...there were so many worms and counterworms loose in the data-net now'

Challenges Of Two-Armed Robots
When the left hand knows what the right hand is doing.

FlexRAM Liquid Metal RAM And One Particular SF Movie Robot
'Its lines wavered, flowed, and then painfully reformed.'

Ulm Sleep Pods For The Homeless
'The lid lifted and she crawled inside...'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.