Science Fiction
Dictionary
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 |
An 'OFF' Switch For The Brain
An "OFF" switch for the brain uses light pulses to shut down neural activity. The method uses the research of Stanford scientist Karl Deisseroth, who discovered how to switch individual brain cells on and off by using light - 'optogenetics'.
(An off switch - for the brain)
In the upper left opsin, the red color shows negative charges
spanning the opsin that facilitated the flow of positive (stimulatory) ions
through the channel into neurons. In the newly engineered channels
(lower right), those negative charges have been changed to positive (blue),
allowing the negatively charged inhibitory chloride ions to flow through.
Now, after almost a decade of research, scientists have been able to shut down the neurons as well as activate them.Mr Deisseroth’s team has now re-engineered its light-sensitive proteins to switch cells much more adequately than before. His findings are presented in the journal Science.
Thomas Insel, director of the National Institute of Mental Health, which funded the study, said this improved “off” switch will help researchers to better understand the brain circuits involved in behavior, thinking and emotion.
“We’re excited about this increased light sensitivity of inhibition in part because we think it will greatly enhance work in large-brained organisms like rats and primates."
The new techniques rely on changing 10 of the amino acids in the optogenetic protein.
“It creates a powerful tool that allows neuroscientists to apply a brake in any specific circuit with millisecond precision, beyond the power of any existing technology,” Mr Insel explained.
This technique could help scientists develop treatments for patients with some brain diseases as it could allow problematic parts of the brain to be switched off with light and tackled with minimal intrusion.
Fans of sf great John Brunner may recall the data-retrieval mode used to access the memories of Nickie Haflinger in Brunner's 1975 masterpiece The Shockwave Rider. In the story, the subject could be "turned on" or "turned off" using this method.
The man in the bare steel chair was as naked as the room's white walls... Tiny adhesive pads held sensors in position at a dozen places on his scalp...From each sensor a lead, fine as gossamer, ran to the... data analysis console...
Not looking up, the girl in white plastic said, "Yes, sir, he's status go."
She headed for the door. Taking a seat at Freeman's invitation, Hartz said doubtfully, "Don't you have to give him a shot or something? He looks pretty thoroughly sedated."
Settling comfortably in his own chair adjacent to the data console, Freeman said, "No, it's not a question of drugs. It's done with induced current in the motor centers. One of our specialties, you know. All I have to do is move this switch and he'll recover consciousness - though not, of course, the power of ambulation. Just enough to let him answer in adequate detail. By the way, before I turn him on, I should fill in what's happening..."
From The Independent.
Scroll down for more stories in the same category. (Story submitted 5/2/2014)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 1 )
Related News Stories - (" Medical ")
BrainBridge Concept Transplant Of Human Head Proposed
'Briquet’s head seemed to think that to find and attach a new body to her head was as easy as to fit and sew a new dress.' - Alexander Belaev (1925)
Natural Gait With Prosthetic Connected To Nervous System
'The leg was to function, in a way, as a servo-mechanism operated by Larry’s brain...' - Charles Recour, 1949.
Brain Implant Is Able To Capture Your Inner Dialogue
'So you see, you can hide nothing from me.'
'Pregnancy Humanoids' From China Replace Moms
'A great many of these synthetic babies were made...' - David H. Keller, 1928.
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Science Fiction
Timeline
1600-1899
1900-1939
1940's 1950's
1960's 1970's
1980's 1990's
2000's 2010's
Current News
The Zapata Air Scooter Would Be Great In A Science Fiction Story
'Betty's slapdash style.'
Thermostabilized Wet Meat Product (NASA Prototype)
There are no orbiting Michelin stars. Yet.
Could Crystal Batteries Generate Power For Centuries?
'Power could be compressed thus into an inch-square cube of what looked like blue-white ice'
India Ponders Always-On Smartphone Location Tracking
'It is necessary... for your own protection.'
Amazon Will Send You Heinlein's Knockdown Cabin
'It's so light that you can set it up in five minutes by yourself...'
Is It Time To Forbid Human Driving?
'Heavy penalties... were to be applied to any one found driving manually-controlled machines.'
Replace The Smartphone With A Connected Edge Node For AI Inference
'Buy a Little Dingbat... electropen, wrist watch, pocketphone, pocket radio, billfold ... all in one.'
Artificial Skin For Robots Is Coming Right Along
'... an elastic, tinted material that had all the feel and appearance of human flesh and epidermis.'
Robot Guard Dog On Duty
I might also be thinking of K-9 from Doctor Who.
Wearable Artificial Fabric Muscles
'It is remarkable that the long leverages of their machines are in most cases actuated by a sort of sham musculature...'
BrainBridge Concept Transplant Of Human Head Proposed
'Briquet’s head seemed to think that to find and attach a new body to her head was as easy as to fit and sew a new dress.'
Google's Nano Banana Pro Presents Handwritten Math Solutions
'...copy was turned out in a charming and entirely feminine handwriting.'
Edible Meat-Like Fungus Like Barbara Hambly's Slunch?
'It was almost unheard of for slunch to spread that fast...'
Sunday Robotics 'Memo' Bot Has Unique Training Glove
'He then started hand movements of definite pattern...'
Woman Marries Computer, Vonnegut's Dream Comes True
'Men are made of protoplasm... Lasts forever.'
Natural Gait With Prosthetic Connected To Nervous System
'The leg was to function, in a way, as a servo-mechanism operated by Larry’s brain...'
