Science Fiction Dictionary
A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

 

Could Young Blood Stop Alzheimer's?

Stanford University researchers have found that changes in the composition of our blood as we age may contribute to the deterioration of memory and other brain functions. Transfusing younger blood into an older body may help keep diseases like Alzheimer's at bay, perhaps indefinitely.

Dr Saul Villeda, who led the research, said he now plans to test the therapy on a mouse model of Alzheimer's disease, in which brain connections break down and cause loss of memory and learning ability.

Speaking at the Society for Neuroscience conference in New Orleans on Tuesday he said: "I think any sort of disease that has that component, there is a chance this might help.

"What I am thinking is if we can address it earlier, when our body still has the control to prevent this from happening, then we might not have to cure Alzheimer's, we might just be able to stop it."

Dr Villeda said older people's blood may damage the brain, and other parts of the body such as the muscles and vital organs, because it contains a greater number of inflammatory proteins in its plasma.

He gave a group of 18-month old mice, which were nearing the end of their lifespans, eight transfusions of younger mice's plasma over the course of a month, adding up to five per cent of their total blood supply.

They were then put in a water maze where they had to learn the route to a hidden platform on which they could stand. Untreated mice usually made two or three wrong turns but the treated group were able to find the right path most of the time.

"They were 18 months old but they were acting much younger, like a four to six-month-old," Dr Villeda said.

He also found that mice given a younger blood supply began to sprout new synapses in their brains, which carry messages between nerve cells, giving them 20 per cent more than the untreated mice on average.

Science fiction Grandmaster Robert Heinlein wrote about this idea in his 1941 novel Methuselah's Children:

"It consists largely in replacing the entire blood tissue in an old person with new, young blood. Old age, so they tell me, is primarily a matter of the progressive accumulation of the waste poisons of metabolism. The blood is supposed to carry them away, but presently the blood gets so clogged with the poisons that the scavenging process doesnít take place properly. Is that right, Doctor Hardy?"

Heinlein remarks in the story that this is a simplified version of the idea, and its purpose was to extend life, rather than just help with diseases. Still, the idea of blood transfusions as a therapy itself is there. Heinlein assumed a developed artificial/cloned blood supply but this is technology we are also working towards (see Blood From Stem Cells: Tru Blood For Real?).

I'd also like to point out that I've turned comments back on and the contact form is also open.

Via Telegraph; also, read about earlier research on how young blood revives aging muscles at Science Daily. Thanks to broklynite for submitting the tip on this story.

Scroll down for more stories in the same category. (Story submitted 10/18/2012)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 3 )

Related News Stories - (" Medical ")

Illustrating Classic Heinlein With AI
'Stasis, cold sleep, hibernation, hypothermia, reduced metabolism, call it what you will - the logistics-medicine research teams had found a way to stack people like cordwood and use them when needed.' - Robert Heinlein, 1956

Brainoware Reservoir Computation Of Biological Neural Networks
'Head cheese. Cultured brains on a slab.' - Peter Watts, 1999.

Forward CarePod The AI Doctor's Office
'It's an old model,' Rawlins said. 'I'm not sure what to do.'

Octopus Suckers Inspire Transdermal Patches
'...a capsule which he placed against his wrist.' - Philip K. Dick, 1960.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

Science Fiction Timeline
1600-1899
1900-1939
1940's   1950's
1960's   1970's
1980's   1990's
2000's   2010's

Current News

Live Stream With Meta-Ban Multimodal Smart Glasses
'...the bug-eyed, opaque gape of her True-Vu lenses.'

'Autonomous' Waymo Improves Driving With Remote Human Operators
'...some bored drone pusher in a remote driving centre has got your life... in his hands.'

Will Whales Be Our First Contact?
'He had piloted the Adastra to its first contact with the civilization of another solar system.'

Heinleinís Controlway - Connected and Automated Vehicle (CAV) Corridor In Michigan
'Well, that's us,' said Lazarus.

SliceIt! Why Not Teach Robots To Use Knives?
'One building now gushed forth smoke and another stench that was unmistakable.'

NYC/Dublin Portal Fails To Meet 'Guardian Of Forever' Standards
I am the Guardian of Forever.

FLOAT Levitating Train On The Moon ala Clarke
'The low-slung monorail car, straddling its single track, bored through the shadows on a slowly rising course.'

Singapore Writers Push Back On LLM Training
'...we've promised him a generous pension from the royalties.'

SpaceX Intros Extravehicular Activity Suit
'Provision had been made to meet the terrific cold which we knew would be encountered the moment we had passed beyond the atmosphere.'

Athena Smart Security Guard Robot With Face Recognition
'You are who we say you are, Dr. Dakin,' Turner said.'

The FLUTE Project - A Huge Liquid Mirror In Space
'It's area, and its consequent light-gathering capacity, was many times greater than any rigid mirror...'

Robot Preachers Found To Undermine Religious Commitment
'Tell me your torments,' the Padre said, in an elderly voice marked with compassion.

CyberCab - Tesla Renames The Robotaxi
'A cybercab dogged their heels...'

SpaceHopper Microgravity Robot Lands On Its Feet
'...a slender-legged tripod surmounted by a spherical body no larger than a football.'

Brin's 1990 Novel Earth Still Full Of Predictions
'... making the point that their likenesses, every move they made, were being transmitted.'

'Whisper Mode' ala Blue Thunder Researched At Bristol
'Forest Lawn.'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.