Science Fiction Dictionary
A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

 

Micromasonry 'Biological Legos' Building New Organs

One of the problems with building your own organs from scratch is getting the 3-dimensional structure right. MIT-Harvard researchers are working on biological legos to grow a 3D organ.

The new technique, called micromasonry, involves tiny blobs of a gel-like material. Each tiny blob contains individual cells; the blobs stick together in a desired structure.


( half sphere of polymer cubes built by MIT-Harvard researchers )

A variety of techniques have been evolved for printing two-dimensional strips of organic matter (see Hungry? Print Yourself Some Bacon and Cultured Meat Straight From The Vat for two approaches).

"That works, but it often lacks a controlled microarchitecture," says Ali Khademhosseini, assistant professor at the MIT-Harvard Division of Health Sciences and Technology (HST), is also an assistant professor at Brigham and Women's Hospital. "You don't get tissues with the same complexity as normal tissues."

Gomez Fernandez and Khademhosseini have used their technique to build tiny tubes that could function as capillaries, which could provide an engineered organ with its blood supply.

The HST researchers built their "biological Legos" by encapsulating cells within a polymer called polyethylene glycol (PEG), which has many medical uses. Their version of the polymer is a liquid that becomes a gel when illuminated, so when the PEG-coated cells are exposed to light, the polymer hardens and encases the cells in cubes with side lengths ranging from 100 to 500 millionths of a meter.

Once the cells are in cube form, they can be arranged in specific shapes using templates made of PDMS, a silicon-based polymer used in many medical devices. Both template and cell cubes are coated again with the PEG polymer, which acts as a glue that holds the cubes together as they pack themselves tightly onto the scaffold surface.

After the cubes are arranged properly, they are illuminated again, and the liquid holding the cubes together solidifies. When the template is removed, the cubes hold their new structure.

SF fans have waited a long time for artificially grown organs; Larry Niven wrote about the idea in his 1968 novel A Gift From Earth.

From Science Daily.

Scroll down for more stories in the same category. (Story submitted 5/16/2010)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 0 )

Related News Stories - (" Medical ")

Illustrating Classic Heinlein With AI
'Stasis, cold sleep, hibernation, hypothermia, reduced metabolism, call it what you will - the logistics-medicine research teams had found a way to stack people like cordwood and use them when needed.' - Robert Heinlein, 1956

Brainoware Reservoir Computation Of Biological Neural Networks
'Head cheese. Cultured brains on a slab.' - Peter Watts, 1999.

Forward CarePod The AI Doctor's Office
'It's an old model,' Rawlins said. 'I'm not sure what to do.'

Octopus Suckers Inspire Transdermal Patches
'...a capsule which he placed against his wrist.' - Philip K. Dick, 1960.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

Science Fiction Timeline
1600-1899
1900-1939
1940's   1950's
1960's   1970's
1980's   1990's
2000's   2010's

Current News

NASA Wants Self-Driving Or Remote-Controlled Vehicles For Lunar Astronauts
'THE autobus turned silently down the wide street of Hydropole. Robot-guided, insulated from noise and cold...'

Elon Musk Says Robotaxis Will Be Ready This August, 2024
'The car had no steering wheel, and no one drove!'

Moonwalkers AI-Controlled Electric Shoes
Now that's power walking that Hugo Gernsback would have approved.

Steve Jobs: 'Capture The Next Aristotle - With AI'
'It was disturbing to think of the Flatline as a construct...'

No Tips! Robotic Food Delivery In Phoenix
'...he rewired the delivery robot so that it would serve him midnight snacks.'

Electric Catamaran 'Explorer Eco 40m' Has 'Solar Skin'
'On went the electric-yacht faster and still faster.'

Orbital Mechanics, The Liftoff, The Turnover, The Retrograde Burn
'...the huge vessel had spun, with a sickening lurch, through a complete half-circle, the instant the power was reversed.'

Harvest Power From Tears And Blinking With Smart Contact Lens
'...he realized that it was not quite a clear lens. Speckles of colored brightness swirled and gathered in it.'

Europa Clipper Plate Carries A Special Message
'...a universal cryptogram — yet it is one which can be interpreted by any intelligent creature on any planet in the Solar System!'

Micro-Robots Are Smallest, Fully Functional
'With a whir, the Scarab shot from the concealing shadows of the corner where it had hidden itself.'

AI Enhances Images Your Brain Sees
'I could have sworn the psychomat showed pictures almost as sharp and detailed as reality itself'

Illustrating Classic Heinlein With AI
'Stasis, cold sleep, hibernation, hypothermia, reduced metabolism, call it what you will - the logistics-medicine research teams had found a way to stack people like cordwood and use them when needed.'

Deflector Plasma Screen For Drones ala Star Wars
'If the enemy persists in attacking or even intensifies their power, the density of the plasma in space will suddenly increase, causing it to reflect most of the incoming energy like a mirror.'

DIY Robotic Hand Made After Loss Of Fingers
'I made them... with the fine work of the watchmaker...'

Cheap Drunk Driver Detection From UofM
"Look, I can drive... Start, darn it!"

Can A Human Land A SpaceX Rocket On Its Tail?
'If she starts to roll sideways — blooey! The underjets only hold you up when they’re pointing down, you know.'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.