Science Fiction
Dictionary
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
 |
Synthehol Sought By Psychopharmacologists
Synthehol is a science-fictional substitute for alcohol that appears on the Star Trek:The Next Generation television series. It allows drinkers to experience all of the enjoyable, intoxicating effects of alcohol without unpleasant side-effects like hang-overs.
(Crusher and Guinan at the ST:TNG bar)
Professor David Nutt, a psychopharmacologist at the University of Bristol in the UK, believes that there is no scientific reason why it cannot be created now.
Alcohol works in the brain mainly by latching onto signalling molecules called GABA-A receptors. There are dozens of subtypes of these; not all of them are associated with specific effects of alcohol. For example, memory loss may occur in conjuction with drinking because alcohol binds to alpha-5, a GABA-A receptor subtype in the hippocampus.
Professor Nutt suggests that if molecules that bind poorly to the bad subtypes like alpha-5 could be developed, it would be possible to retain the pleasant effects of alcohol without the bad side-effects.
Some "partial agonists" of GABA-A receptors already exist; bretazenil and pagoclone were developed as anti-anxiety drugs. These drug molecules are instantly reversible by the flumazenil, used as an antidote to overdoses of tranquillisers.
Another element of the "synthehol" alcohol substitute would be an NMDA antagonist such as dizoclipine, originally developed as a drug for stroke. Alcohol inhibits NMDA receptors, which are part of a general excitatory signalling circuit.
Perhaps most interesting is the idea that problems like cirrhosis of the liver could be eliminated by altering the composition of alcoholic beverages. Professor Nutt will be publishing this idea in the Journal of Psychopharmacology next month.
Science-fictional-beverage enthusiasts should take a look at Programmable Soda, an amazing prediction by UK sf writer Jeff Noon. Roboticists with an interest in alcohol should read Methanol-Powered Robot Muscles - Bend It Like Bender.
For the science part, read All the pleasures of alcohol, with no downsides; for the sf part, read more about synthehol. Thanks to Greg for providing the story tip and the sf reference.
Scroll down for more stories in the same category. (Story submitted 4/11/2006)
Follow this kind of news @Technovelgy.| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 2 )
Related News Stories - (" Medical ")
Natural Gait With Prosthetic Connected To Nervous System
'The leg was to function, in a way, as a servo-mechanism operated by Larry’s brain...' - Charles Recour, 1949.
Brain Implant Is Able To Capture Your Inner Dialogue
'So you see, you can hide nothing from me.'
'Pregnancy Humanoids' From China Replace Moms
'A great many of these synthetic babies were made...' - David H. Keller, 1928.
Bacteria Turns Plastic Into Pain Relief? That Gives Me An Idea.
'I guess there's nobody round this table who doesn't have a Crosswell [tapeworm] working for him in the small intestine.'
Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.
Science Fiction
Timeline
1600-1899
1900-1939
1940's 1950's
1960's 1970's
1980's 1990's
2000's 2010's
Current News
Natural Gait With Prosthetic Connected To Nervous System
'The leg was to function, in a way, as a servo-mechanism operated by Larry’s brain...'
Woman Marries Computer, Vonnegut's Dream Comes True
'Men are made of protoplasm... Lasts forever.'
Spidery 'Walk Me' Toyota Autonomous Wheel Chair Like Star Wars
Walk along with the emperor.
Dancing Robots Taught Dance Moves
'A clockwork figure would be the thing for you...'
Proof Of Robothood - Not A Person
'Who are you people? - Show 'em.'
Indonesian Clans Battle
'The observation vehicle was of that peculiar variety used in conveying a large number of people across rough terrain.'
The 'Last Mile' In China Crowded With Delivery Robots
Yes, it's a delivery robot. On wheels.
Tornyol Microdrone Kills Mosquitoes
'The real border was defended by... a swarm of quasi-independent aerostats.'
PLATO Spacecraft, Hunter Of Habitable Planets, Now Ready
'I ... set my automatic astronomical instruments to searching for a habitable planet.'
Factory Humanoid Robots Built By Humanoid Robots
'...haven't you a section of the factory where only robot labor is employed?'
iPhone Air Fulfils Jobs' Promise From 2007 - A Giant Screen!
'... oblongs were all over the floor and surfaces.'
ChatGPT Now Participates in Group Chats
'...the city was their laboratory in human psychology.'
iPhone Pocket All Sold Out!
'A long, strong, slender net...'
Did The Yautja Have These First?
What a marvel of ingenuity the little device was!
Jetson ONE Air Races Begin, Can Air Polo Be Far Behind?
'If you're one of those rarities who haven't attended a rocket-polo "carnage", let me tell you it's a colorful affair.'
Will Space Stations Have Large Interior Spaces Again?
'They filed clumsily into the battleroom, like children in a swimming pool for the first time, clinging to the handholds along the side.'
