 |
Science Fiction
Dictionary
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
|
 |
Toxoplasma Gondii Parasite Mind Control
Half of the world's human population is infected with Toxoplasma. Parasites in the body - and the brain. Remember that.
Toxoplasma gondii is a common parasite found in the gut of cats; it sheds eggs that are picked up by rats and other animals that are eaten by cats. Toxoplasma forms cysts in the bodies of the intermediate rat hosts, including the brain. Since cats don't want to eat dead, decaying prey, Toxoplasma takes the evolutionarily sound course of being a "good" parasite, leaving the rats perfectly healthy. Or are they?

(Toxoplasma gondii)
Oxford scientists discovered that the minds of the infected rats have been subtly altered. In a series of experiments, they demonstrated that healthy rats will prudently avoid areas that have been doused with cat urine. In fact, when scientists test anti-anxiety drugs on rats, they use a whiff of cat urine to induce neurochemical panic. However, it turns out that Toxoplasma-ridden rats show no such reaction. In fact, some of the infected rats actually seek out the cat urine-marked areas again and again. The parasite alters the mind (and thus the behavior) of the rat for its own benefit.
If the parasite can alter rat behavior, does it have any effect on humans? Dr. E. Fuller Torrey (Associate Director for Laboratory Research at the Stanley Medical Research Institute) noticed links between Toxoplasma and schizophrenia in human beings, approximately three billion of whom are infected with T. gondii:
- Toxoplasma infection is associated with damage to astrocytes, glial cells which surround and support neurons. Schizophrenia is also associated with damage to astrocytes.
- Pregnant women with high levels of antibodies to Toxoplasma are more likely to give birth to children who will develop schizophrenia.
- Human cells raised in petri dishes, and infected with Toxoplasma, will respond to drugs like haloperidol; the growth of the parasite stops. Haloperidol is an antipsychotic, used to treat schizophrenia.
Dr. Torrey got together with the Oxford scientists, to see if anything could be done about those parasite-controlled rats who were driven to hang around cat urine-soaked corners (waiting for cats). According to a recent press release, it turns out that haloperidol restores the rat's healthy fear of cat urine. In fact, antipsychotic drugs were as effective as pyrimethamine, a drug that specifically eliminates Toxoplasma.
Are parasites like Toxoplasma subtly altering human behavior? As it turns out, science fiction writers have been thinking about whether or not parasites could alter a human being's behavior, or even take control of a person. In his 1951 novel The Puppet Masters, Robert Heinlein wrote about alien parasites the size of dinner plates that took control of the minds of their hosts, flooding their brains with neurochemicals. In this excerpt, a volunteer strapped to a chair allows a parasite to be introduced; the parasite rides him, taking over his mind. Under these conditions, it is possible to interview the parasite; however, it refuses to answer until zapped with a cattle prod.
He reached past my shoulders with a rod. I felt a shocking, unbearable pain. The room blacked out as
if a switch had been thrown.. I was split apart
by it; for the moment I was masterless.
The pain left, leaving only its searing memory behind. Before I could speak, or even think coherently
for myself, the splitting away had ended and I was again safe in the arms of my master...
The panic that possessed me washed away; I was again filled with an unworried sense of well being...
"What are you?"
"We are the people... We have studied you and we know your ways... We come," I went on, "to bring you peace.. and contentment-and the joy of-of surrender." I hesitated again; "surrender" was not the right word. I struggled with it the way one struggles with a poorly grasped foreign language.
"The joy," I repeated, "-the joy of . . .nirvana." That was it; the word fitted. I felt like a dog being patted
for fetching a stick; I wriggled with pleasure.
Still not sure that parasites can manipulate the behavior of host organisms? Consider these other cases:
- The lancet fluke Dicrocoelium dendriticum forces its ant host to attach to the tips of grass blades, the easier to be eaten. The fluke needs to get into the gut of a grazing animal to complete its life cycle.
- The fluke Euhaplorchis californiensis causes fish to shimmy and jump so wading birds will grab them and eat them, for the same reason.
- Hairworms, which live inside grasshoppers, sabotage the grasshopper's central nervous system, forcing them to jump into pools of water, drowning themselves. Hairworms then swim away from their hapless hosts to continue their life cycle.
Not all science-fictional parasites are harmful; read about the Crosswell tapeworm from Brian Aldiss' 1969 story Super-Toys Last All Summer Long, which keeps people who overeat from becoming obese. Not to mention robots based on parasites. Read press release on evidence for link between Toxoplasma and schizophrenia, Suicidal grasshoppers. Story via blogger
Carl Zimmer and his readers.
Scroll down for more stories in the same category. (Story submitted 2/7/2006)
Follow this kind of news @Technovelgy.
| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |
Would
you like to contribute a story tip?
It's easy:
Get the URL of the story, and the related sf author, and add
it here.
Comment/Join discussion ( 45 )
Related News Stories -
("
Medical
")
Bacteria Turns Plastic Into Pain Relief? That Gives Me An Idea.
'I guess there's nobody round this table who doesn't have a Crosswell [tapeworm] working for him in the small intestine.'
Heart Patches Grown In The Lab Repair Hearts
I'm hoping that this procedure becomes a normal part of medical practice!
Pixel Watch 'Loss of Pulse Detection' And Philip K. Dick
'He carried on his person a triggering mechanism sensitive to his heartbeat.' - Philip K. Dick, 1965.
ErythroMer Artificial Blood
'My chemists are all working on the preparation of the artificial blood.' - Dr. David H. Keller, M.D.
Technovelgy (that's tech-novel-gee!)
is devoted to the creative science inventions and ideas of sf authors. Look for
the Invention Category that interests
you, the Glossary, the Invention
Timeline, or see what's New.
|
 |
Science Fiction
Timeline
1600-1899
1900-1939
1940's 1950's
1960's 1970's
1980's 1990's
2000's 2010's
Current News
LLM 'Cognitive Core' Now Evolving
'Their only check on the growth and development of Vulcan 3 lay in two clues: the amount of rock thrown up to the surface... and the amount of the raw materials and tools and parts which the computer requested.'
Has Elon Musk Given Up On Mars?
'There ain't no such thing as a free lunch.'
Bacteria Turns Plastic Into Pain Relief? That Gives Me An Idea.
'I guess there's nobody round this table who doesn't have a Crosswell [tapeworm] working for him in the small intestine.'
When Your Child's Best Friend Is An AI
'Figments of his mind in one sense, of course, for he had shaped them...'
China's Drone Mothership Can Carry 100 Drones
'So the parent drone carries a spotter that it launches...'
Drones Recharge In Mid-Air Like Jets Refuel!
'...nurse drones that would cruise around dumping large amounts of power into randomly selected pods.'
Australian Authors Reject AI Training Of Llama
'It's done with a flip of the third joint of the tentacle on the down beat.'
Is China Mining Helium-3 On The Moon's Farside?
'...for months Grantline bores had dug into the cliff.'
Maybe It's Too Soon To Require Autonomous Mode
'I hope all those other cars are on automatic,' he said anxiously.
Is Agentic AI The Wrong Kind Of Smartness?
'It’s smart enough to go wrong in very complicated ways, but not smart enough to help us find out what’s wrong.'
Heat Waver - The First Ever Combo Solar Collector And Wind Turbine
'...like a spray of tulips mounted fanwise.'
Tesla 'Fleet Response Agents' Bolster FSD Autonomy
'You hate the whole idea that some bored drone pusher in a remote driving centre has got your life... in his hands.'
Mori3 Autonomous Shapeshifting Robot
'My homeland is being threatened by the Replicators. Thus far all attempts to stop them have failed.'
Tesla Seeks 'Tesla Robotaxi' And 'Robobus' Trademarks Ignoring Prior Art
'A robobus had just rolled up to the curb.'
Scary Grid Safety Robots
'The ultimate horror for our paranoid culture...'
Does AI Provide A Way Forward For Talk Therapy
'And there in the next room by the sofa sat a familiar suitcase, that of his psychiatrist Dr. Smile.'
More SF in the News Stories
More Beyond Technovelgy science news stories
|
 |