Science Fiction Dictionary
A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z

 

Mini-Livers Made By 3D Printer

Tiny livers have been printed in the lab by Organovo in San Diego, California. These mini-livers are just four millimeters across and half a millimeter deep, but they perform most of the functions of real livers.


(Organovo 3D prints mini-livers)

To create them, a printer builds up about 20 layers of hepatocytes and stellate cells – two major types of liver cell. Crucially, it also adds cells from the lining of blood vessels. These form a delicate mesh of channels that supply the liver cells with nutrients and oxygen, allowing the tissue to live for five days or longer. The cells come from spare tissue removed in operations and biopsies.

Existing liver assays, based on single or double layers of cells, only last two days and don't have the same range of functions as the micro-discs.

The realistic structure and functioning of the mini-livers make them good predictors of the toxicity of drugs and other substances. They produce albumin, the liver protein that bulks up blood and ferries hormones, salts and drugs throughout the body. They also make cholesterol, which carries fat in the bloodstream, and produce major detoxification enzymes, called cytochrome P450s, that metabolise drugs in the liver.

Artificially grown livers for transplantation was one of the issues discussed by science fiction writer Larry Niven in his 1968 novel A Gift from Earth:

...For a while your colonists will have to come up to the Hospital to get treatment with the ramrobot symbiots, but eventually we can build culture tanks in Gamma and Delta and Eta."
(Read more about Larry Niven's artificially grown organs)

Via New Scientist.

Scroll down for more stories in the same category. (Story submitted 4/29/2013)

Follow this kind of news @Technovelgy.

| Email | RSS | Blog It | Stumble | del.icio.us | Digg | Reddit |

Would you like to contribute a story tip? It's easy:
Get the URL of the story, and the related sf author, and add it here.

Comment/Join discussion ( 7 )

Related News Stories - (" Medical ")

Illustrating Classic Heinlein With AI
'Stasis, cold sleep, hibernation, hypothermia, reduced metabolism, call it what you will - the logistics-medicine research teams had found a way to stack people like cordwood and use them when needed.' - Robert Heinlein, 1956

Brainoware Reservoir Computation Of Biological Neural Networks
'Head cheese. Cultured brains on a slab.' - Peter Watts, 1999.

Forward CarePod The AI Doctor's Office
'It's an old model,' Rawlins said. 'I'm not sure what to do.'

Octopus Suckers Inspire Transdermal Patches
'...a capsule which he placed against his wrist.' - Philip K. Dick, 1960.

 

Google
  Web TechNovelgy.com   

Technovelgy (that's tech-novel-gee!) is devoted to the creative science inventions and ideas of sf authors. Look for the Invention Category that interests you, the Glossary, the Invention Timeline, or see what's New.

 

 

 

 

Science Fiction Timeline
1600-1899
1900-1939
1940's   1950's
1960's   1970's
1980's   1990's
2000's   2010's

Current News

Europa Clipper Plate Carries A Special Message
'...a universal cryptogram — yet it is one which can be interpreted by any intelligent creature on any planet in the Solar System!'

Micro-Robots Are Smallest, Fully Functional
'With a whir, the Scarab shot from the concealing shadows of the corner where it had hidden itself.'

AI Enhances Images Your Brain Sees
'I could have sworn the psychomat showed pictures almost as sharp and detailed as reality itself'

Illustrating Classic Heinlein With AI
'Stasis, cold sleep, hibernation, hypothermia, reduced metabolism, call it what you will - the logistics-medicine research teams had found a way to stack people like cordwood and use them when needed.'

Deflector Plasma Screen For Drones ala Star Wars
'If the enemy persists in attacking or even intensifies their power, the density of the plasma in space will suddenly increase, causing it to reflect most of the incoming energy like a mirror.'

DIY Robotic Hand Made After Loss Of Fingers
'I made them... with the fine work of the watchmaker...'

Cheap Drunk Driver Detection From UofM
"Look, I can drive... Start, darn it!"

Can A Human Land A SpaceX Rocket On Its Tail?
'If she starts to roll sideways — blooey! The underjets only hold you up when they’re pointing down, you know.'

Robot Snakes No Longer Stopped By Stairs
'...she dropped her hands from the wheel, took the robot snake from his box.'

Has Turkey Been Stealing Rain From Iran?
Can one country take another's rain?

We Need To Build Anti-Drone Systems For Civilian Spaces
'the real border was defended by ...a swarm of quasi-independent aerostats...'

SensorWake Scent-Based Alarm Clock
'The odalarm awoke Jorj X. McKie with a whiff of lemon.'

AI Worms That Spread
'...there were so many worms and counterworms loose in the data-net now'

Challenges Of Two-Armed Robots
When the left hand knows what the right hand is doing.

FlexRAM Liquid Metal RAM And One Particular SF Movie Robot
'Its lines wavered, flowed, and then painfully reformed.'

Ulm Sleep Pods For The Homeless
'The lid lifted and she crawled inside...'

More SF in the News Stories

More Beyond Technovelgy science news stories

Home | Glossary | Invention Timeline | Category | New | Contact Us | FAQ | Advertise |
Technovelgy.com - where science meets fiction™

Copyright© Technovelgy LLC; all rights reserved.