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"People ask me how I do research for my science fiction. The answer is, I never do any research. I just enjoy reading the stuff, and some of it sticks in my mind and fits into the stories."
- Frederik Pohl

Monsters Manufactured  
  Dr. Moreau demonstrates the plasticity of the organic form.  

Dr. Moreau performs experiments on animals, always testing the limits of what is possible, to transform them into something more man-like.

I am only beginning. Those are trivial cases of alteration. Surgery can do better things than that. There is building up as well as breaking down and changing. You have heard, perhaps, of a common surgical operation resorted to in cases where the nose has been destroyed: a flap of skin is cut from the forehead, turned down on the nose, and heals in the new position. This is a kind of grafting in a new position of part of an animal upon itself. Grafting of freshly obtained material from another animal is also possible,--the case of teeth, for example. The grafting of skin and bone is done to facilitate healing: the surgeon places in the middle of the wound pieces of skin snipped from another animal, or fragments of bone from a victim freshly killed. Hunter's cock-spur--possibly you have heard of that--flourished on the bull's neck; and the rhinoceros rats of the Algerian zouaves are also to be thought of,--monsters manufactured by transferring a slip from the tail of an ordinary rat to its snout, and allowing it to heal in that position."

"Monsters manufactured!" said I. "Then you mean to tell me--"

"Yes. These creatures you have seen are animals carven and wrought into new shapes. To that, to the study of the plasticity of living forms, my life has been devoted. I have studied for years, gaining in knowledge as I go. I see you look horrified, and yet I am telling you nothing new. It all lay in the surface of practical anatomy years ago, but no one had the temerity to touch it. It is not simply the outward form of an animal which I can change. The physiology, the chemical rhythm of the creature, may also be made to undergo an enduring modification,--of which vaccination and other methods of inoculation with living or dead matter are examples that will, no doubt, be familiar to you. A similar operation is the transfusion of blood,--with which subject, indeed, I began. These are all familiar cases. Less so, and probably far more extensive, were the operations of those mediaeval practitioners who made dwarfs and beggar-cripples, show-monsters,--some vestiges of whose art still remain in the preliminary manipulation of the young mountebank or contortionist. Victor Hugo gives an account of them in 'L'Homme qui Rit.'--But perhaps my meaning grows plain now. You begin to see that it is a possible thing to transplant tissue from one part of an animal to another, or from one animal to another; to alter its chemical reactions and methods of growth; to modify the articulations of its limbs; and, indeed, to change it in its most intimate structure.

"And yet this extraordinary branch of knowledge has never been sought as an end, and systematically, by modern investigators until I took it up! Some such things have been hit upon in the last resort of surgery; most of the kindred evidence that will recur to your mind has been demonstrated as it were by accident,--by tyrants, by criminals, by the breeders of horses and dogs, by all kinds of untrained clumsy-handed men working for their own immediate ends. I was the first man to take up this question armed with antiseptic surgery, and with a really scientific knowledge of the laws of growth. Yet one would imagine it must have been practised in secret before. Such creatures as the Siamese Twins--And in the vaults of the Inquisition. No doubt their chief aim was artistic torture, but some at least of the inquisitors must have had a touch of scientific curiosity."

Technovelgy from The Island of Dr. Moreau, by H.G. Wells.
Published by Garden City in 1896
Additional resources -

Wells also makes this remark about the ethics of the scientist:

The thing before you is no longer an animal, a fellow-creature, but a problem! Sympathetic pain,--all I know of it I remember as a thing I used to suffer from years ago. I wanted--it was the one thing I wanted--to find out the extreme limit of plasticity in a living shape."

"But," said I, "the thing is an abomination--"

"To this day I have never troubled about the ethics of the matter," he continued. "The study of Nature makes a man at last as remorseless as Nature.

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Additional resources:
  More Ideas and Technology from The Island of Dr. Moreau
  More Ideas and Technology by H.G. Wells
  Tech news articles related to The Island of Dr. Moreau
  Tech news articles related to works by H.G. Wells

Monsters Manufactured-related news articles:
  - Mouse With Human Brain May Live
  - Cambrian Genetics Says 'Print Your Own Genetically Unique Creature'

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